797035-11-1
中文名稱(chēng)
BETA-SECRETASE INHIBITOR IV
英文名稱(chēng)
BETA-SECRETASE INHIBITOR IV
CAS
797035-11-1
分子式
C31H38N4O5S
分子量
578.72
MOL 文件
797035-11-1.mol
更新日期
2026/06/22 10:35:03
797035-11-1 結(jié)構(gòu)式
基本信息
中文別名
BACE-1抑制劑化合物 T13434
英文別名
BACE-1 inhibitorβ-Secretase Inhibitor IV
β-Secretase Inhibitor IV
γ-Secretase Inhibitor IV
BETA-SECRETASE INHIBITOR IV
N-((1S,2R)-1-BENZYL-3-CYCLOPROPYLAMINO-2-HYDROXY-PROPYL)-5-(METHANESULFONYL-METHYL-AMINO)-N'-((R)-1-PHENYL-ETHYL)-ISOPHTHALAMIDE
N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl)-5-(N-methylmethylsulfonamido)-N3-((R)-1-phenylethyl)isophthalamide
3-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-1-N-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide
1,3-BENZENEDICARBOXAMIDE, N1-[(1S,2R)-3-(CYCLOPROPYLAMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N3-[(1R)-1-PHENYLETHYL]-
物理化學(xué)性質(zhì)
密度1.30±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
酸度系數(shù)(pKa)13.72±0.46(Predicted)
形態(tài)結(jié)晶固體
顏色Off-white to light yellow
InChIKeyVPNIQGRFZCTBEZ-SPTGULJVSA-N
SMILESO=C(C1=CC(C(N[C@@H](CC2=CC=CC=C2)[C@H](O)CNC3CC3)=O)=CC(N(S(C)(=O)=O)C)=C1)N[C@H](C)C4=CC=CC=C4