一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

返回ChemicalBook首頁(yè)>CAS數(shù)據(jù)庫(kù)列表>79994-24-4

79994-24-4

中文名稱(chēng) DYNORPHIN A (1-10)
英文名稱(chēng) H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OH
CAS 79994-24-4
分子式 C57H91N19O12
分子量 1234.45
MOL 文件 79994-24-4.mol
更新日期 2026/07/10 13:20:57
79994-24-4 結(jié)構(gòu)式 79994-24-4 結(jié)構(gòu)式

基本信息

中文別名
DYNORPHIN A (1-10), PORCINE,YGGFLRRIRP
英文別名
YGGFLRRIRP
DYNORPHIN A (1-10)
Porcine dynorphin A(1-10)
DYNORPHIN A (1-10), PORCINE
dynorphin A, porcine, fragment 1-10
TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO
dynorphin A fragment 1-10 porcine*sequence
H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-ILE-ARG-PRO-OH
DYNORPHIN A (1-10) SYNTHETIC >97% OPIOID AGONIST

物理化學(xué)性質(zhì)

儲(chǔ)存條件-15°C
溶解度Soluble in DMSO
序列Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro

常見(jiàn)問(wèn)題列表

生物活性
Dynorphin A (1-10) 是一種內(nèi)源性的阿片樣神經(jīng)肽,與 κ 阿片受體 (κ-opioid receptor) 結(jié)合。Dynorphin A (1-10) 也阻斷 NMDA 激活的電流,IC50 為 42.0 μM。
靶點(diǎn)

κ-opioid receptor
NMDA receptor

體外研究

Dynorphin A (1-10) binds in the transmembrane domain of the κ-receptor. The non-opioid actions of various forms of Dynorphin A (DynA) are examined on N-methyl-D-aspartate (NMDA) receptor channels in isolated rat trigeminal neurons using the whole-cell patch recording technique. All the dynorphins tested blocked NMDA-activated currents. The blocking actions are voltage-independent. The IC 50 is 42.0 μM for DynA(1-10). To determine if shorter dynorphins have the similar blocking property, we examined the action of DynA(1-10) at different membrane potentials. DynA(1-10) blocks I NMDA to a similar extent as the membrane potentials changed from -80 to +60 mV. Thus, despite a 160-fold difference in the apparent affinities, DynA(1-32) and DynA(1-10) both exert voltage-independent actions on NMDA receptors.

"79994-24-4" 相關(guān)產(chǎn)品信息
85006-82-2 80448-90-4 72957-38-1 126050-26-8 84376-30-7 75106-70-6
蕲春县| 达日县| 富宁县| 伊川县| 宾阳县| 馆陶县| 旌德县| 邹城市| 庄浪县| 临夏县| 阿拉善右旗| 德惠市| 靖宇县| 吉水县| 南宁市| 长岛县| 泰安市| 东丰县| 鄂托克前旗| 城固县| 河西区| 六盘水市| 黔东| 顺平县| 皋兰县| 财经| 温泉县| 镇康县| 广饶县| 颍上县| 肥乡县| 罗定市| 宣武区| 南涧| 郴州市| 邯郸县| 彭泽县| 土默特右旗| 明水县| 海原县| 建阳市|