802918-36-1
中文名稱
西那卡塞雜質(zhì)9
英文名稱
Cinacalcet IMpurity 9
CAS
802918-36-1
分子式
C22H24F3N
分子量
359.44
MOL 文件
802918-36-1.mol
更新日期
2025/11/25 13:17:00
802918-36-1 結(jié)構(gòu)式
基本信息
中文別名
西那卡塞雜質(zhì)9西那卡特雜質(zhì)9
辛那卡塞特雜質(zhì)I
西那卡塞雜質(zhì)72
西那卡塞特雜質(zhì)I
西那卡塞二氫雜質(zhì)2
鹽酸西那卡塞二氫雜質(zhì)2
西那卡塞雜質(zhì)16(單體)
英文別名
Cinacalcet-13Cinacalcet IMpurity 9
CicalcetDihydroImpurity2HCl
Cinacalcet Dihydro Impurity 2 HCl
(R)-N-(1-(5,6-dihydronaphthalen-1-yl)ethyl)-
N-[(1R)-1-(5,6-dihydronaphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine
(αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine
1-Naphthalenemethanamine, 5,6-dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-, (αR)-
N-(1-(7,8-dihydrophthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-aminehydrochloride
Cinacalcet impurity 13/Cinacalcet Dihydro Impurity 2 HCl/(R)-N-(1-(5,6-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl) phenyl)propan-1-amine hydrochloride
所屬類別
分析化學(xué)：藥典標(biāo)準(zhǔn)品和雜質(zhì)標(biāo)準(zhǔn)品應(yīng)用領(lǐng)域
用途一
(αR)-5,6-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine is synthetically prepared though a double bond migration in Heck reaction during the preparation of cinacalcet congeners. This enantiomerically pure material is seperated from its counter part, (αR)-7,8-Dihydro-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine (D455330) using HPLC.