81944-08-3
中文名稱
化合物 T13670
英文名稱
1(3H)-Isobenzofuranone, 3-butylidene-4,5-dihydro-, (3E)-
CAS
81944-08-3
分子式
C12H14O2
分子量
190.24
MOL 文件
81944-08-3.mol
81944-08-3 結(jié)構(gòu)式
常見問題列表
生物活性
(E)-Ligustilide 是從當(dāng)歸中分離得到的，具有腎臟保護(hù)作用。體外研究
(E)-Ligustilide (50?μM; 24-72 hours) decreases HK-2 cell survival to 86%, to 67% and to 49% for 24, 48 or 72?hours incubation, respectively.(E)-Ligustilide (50?μM; 48-72 hours) alone decreases the metabolic activity to 87±6% and 71±8% after 48 and 72?h incubation, respectively, as compared to the control condition in HK-2 cells.
Cell Viability Assay
| Cell Line: | HK-2 cell |
| Concentration: | 50 μM |
| Incubation Time: | 24 hours, 48 hours and 72 hours |
| Result: | Decreased cell survival as a dose-dependent manner. |