863239-60-5
中文名稱
奧貝膽酸雜質(zhì)8
英文名稱
Glyco Obeticholic acid
CAS
863239-60-5
分子式
C28H47NO5
分子量
477.69
MOL 文件
863239-60-5.mol
更新日期
2024/04/28 11:58:04
863239-60-5 結(jié)構(gòu)式
基本信息
中文別名
乙醇-油酸甘氨酰奧貝膽酸
英文別名
Glyco Obeticholic acidGlycine, N-[(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-24-oxocholan-24-yl]-
Obeticholic Acid Impurity 3/Glyco-Obeticholic Acid/Glycine 6-Ethylchenodeoxycholate/((R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoyl)glycine
所屬類別
有機原料：羧酸類化合物及衍生物物理化學性質(zhì)
沸點666.4±40.0 °C(Predicted)
密度1.125±0.06 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度DMSO: slightly soluble; Methanol: slightly soluble
酸度系數(shù)(pKa)3.58±0.10(Predicted)
形態(tài)固體
穩(wěn)定性吸濕性
奧貝膽酸雜質(zhì)8價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2025/12/22 | HY-135400 | Glyco-Obeticholic acid | 863239-60-5 | 1 mg | 780元 |
| 2025/12/22 | HY-135400 | 奧貝膽酸雜質(zhì)8 Glyco-Obeticholic acid | 863239-60-5 | 5mg | 1872元 |
| 2025/12/22 | HY-135400 | 奧貝膽酸雜質(zhì)8 Glyco-Obeticholic acid | 863239-60-5 | 10 mg | 2808元 |
常見問題列表
生物活性
Glyco-obeticholic acid 是?；撬岬幕钚源x物。Obeticholic Acid 是一種口服生物可利用的法尼樣X受體 (FXR) 激動劑。體外研究
Obeticholic acid is conjugated with glycine in the liver to form glycol-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate glyco-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces.