865305-30-2
中文名稱
5-(5-碘-2-異丙基-4-甲氧基苯氧基)嘧啶-2,4-二胺
英文名稱
2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-
CAS
865305-30-2
分子式
C14H17IN4O2
分子量
400.21
MOL 文件
865305-30-2.mol
更新日期
2026/07/17 13:02:21
865305-30-2 結(jié)構(gòu)式
基本信息
中文別名
5-(5-碘-2-異丙基-4-甲氧基苯氧基)嘧啶-2,4-二胺5-[5-碘-4-甲氧基-2-(1-甲基乙基)苯氧基]-2,4-嘧啶二胺
英文別名
Ro 4AF 353
CS-2469
CHEMBL526307
AF-353 (Ro-4)
CHEMBL526307
AF 353
AF353
5-[5-Iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2,4-pyrimidinediamine
2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-
5-{[5-iodo-2-(1-Methylethyl)-4-(Methyloxy)phenyl]oxy}-2,4-pyriMidinediaMine
5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2,4-pyrimidinediamine hydrochloride Ro 4 hydrochloride
所屬類別
生物化工：激動(dòng)劑抑制劑物理化學(xué)性質(zhì)
沸點(diǎn)510.2±60.0 °C(Predicted)
密度1.619±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO : ≥ 32 mg/mL (79.96 mM)
酸度系數(shù)(pKa)6.89±0.10(Predicted)
形態(tài)Solid
顏色Light brown to brown
應(yīng)用領(lǐng)域
用途1
一種p2x3受體拮抗劑。AF353 is a P2X3 receptor antagonist. Antagonism of the P2X3 receptor is one of the potential therapeutic strategies for the management of neuropathic pain because P2X3 receptors are predominantly localized on small to medium diameter C- and Aδ-fiber primary afferent neurons, which are related to the pain-sensing system.5-(5-碘-2-異丙基-4-甲氧基苯氧基)嘧啶-2,4-二胺價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/07/06 | S0405 | 5-(5-碘-2-異丙基-4-甲氧基苯氧基)嘧啶-2,4-二胺 AF-353 | 865305-30-2 | 5mg | 895.67元 |
| 2026/07/06 | S0405 | 5-(5-碘-2-異丙基-4-甲氧基苯氧基)嘧啶-2,4-二胺 AF-353 | 865305-30-2 | 10mM (1mL in DMSO) | 958.23元 |
| 2026/07/06 | S0405 | 5-(5-碘-2-異丙基-4-甲氧基苯氧基)嘧啶-2,4-二胺 AF-353 | 865305-30-2 | 25mg | 3150.4元 |