92307-52-3
中文名稱
CRF,CRH,促腎上腺皮質(zhì)激素釋放激素
英文名稱
CRF (BOVINE)
CAS
92307-52-3
分子式
C206H340N60O63S
分子量
4697.33
MOL 文件
92307-52-3.mol
更新日期
2025/02/24 09:40:46
92307-52-3 結(jié)構(gòu)式
基本信息
中文別名
牛ACTH釋放因子牛促腎上腺皮質(zhì)激素釋放激素
促腎上腺皮質(zhì)激素釋放因子(牛)
CRF,CRH,促腎上腺皮質(zhì)激素釋放激素
牛促腎上腺皮質(zhì)激素釋放激素, ≥90% (HPLC)
英文別名
CRFCRH
CRF (BOVINE)
PubChem ID: 71581479
CRF (BOVINE) USP/EP/BP
Bovine ACTH-releasing factor
CORTICOTROPIN RELEASING FACTOR BOVINE
Cattle corticotropin-releasing horMone
Corticotropin-releasing factor (cattle)
Corticotropin Releasing Factor bovine,CRF, CRH
所屬類別
生物化工：多肽物理化學(xué)性質(zhì)
儲(chǔ)存條件−20°C
溶解度溶于二甲基亞砜
形態(tài)固體
序列Ser-Gln-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Thr-Lys-Ala-Asp-Gln-Leu-Ala-Gln-Gln-Ala-His-Asn-Asn-Arg-Lys-Leu-Leu-Asp-Ile-Ala-NH2
CRF,CRH,促腎上腺皮質(zhì)激素釋放激素價(jià)格(試劑級)
| 報(bào)價(jià)日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
| 2025/05/22 | XW923075232 | 牛促腎上腺皮質(zhì)激素釋放激素 | 92307-52-3 | 5MG | 2394元 |
| 2025/05/22 | XW923075231 | 牛促腎上腺皮質(zhì)激素釋放激素 | 92307-52-3 | 1MG | 515元 |
常見問題列表
生物活性
CRF, bovine 是一種有效的 CRF 受體激動(dòng)劑，能夠取代 [125I-Tyr]ovine CRF，Ki 值為3.52 nM。靶點(diǎn)
Ki: 3.52 nM (CRF receptor)
體外研究
CRF, bovine is a potent agonist of CRF receptor, and displaces [ 125 I-Tyr]ovine CRF with a K i of 3.52 nM. CRF shows pEC 50 s of 11.16, 8.53 and 8.70 for human CRF 1 , human CRF 2 and rat CRF 2α . CRF is released from hypothalamic-pituitary-adrenal (HPA) axis induced by stress, and leads to production of glucocorticoids which down regulate immune responses. CRF also has proinflammatory effects. CRF affects brain microvessel endothelial cells (BMEC) structure or function, CRF (100 nM) significantly increases cAMP in BMEC.