925448-93-7
925448-93-7 結(jié)構(gòu)式
基本信息
中文別名
化合物CERLAPIRDINEN,N-二甲基-3-[[3-(1-萘?；酋；?-1H-吲唑-5-基]氧基]-1-丙胺
英文別名
SAM-531WAY-262
PF05212365
WAY-262,531
P -05212365
PF-05212365
Cerlapirdine
N,N-Dimethyl-3-[[3-(1-naphthalenylsulfonyl)-1H-indazol-5-yl]oxy]-1-propanamine
1-Propanamine, N,N-dimethyl-3-[[3-(1-naphthalenylsulfonyl)-1H-indazol-5-yl]oxy]-
antagonist,inhibit,5-HT Receptor,5-hydroxytryptamine,5-HT6,oral,Cerlapirdine,PF 05212365,selective,Alzheimer's disease,Serotonin Receptor,5-hydroxytryptamine Receptor,Inhibitor
物理化學(xué)性質(zhì)
沸點662.9±45.0 °C(Predicted)
密度1.300±0.06 g/cm3(Predicted)
儲存條件4°C, protect from light
溶解度DMSO : 41.67 mg/mL (101.76 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 60°C)
酸度系數(shù)(pKa)9.70±0.40(Predicted)
形態(tài)Solid
顏色Off-white to yellow
常見問題列表
概述
Cerlapirdine (SAM-531, PF-05212365) 是一種選擇性和有效的 5-羥色胺 6 (5-HT6) 受體的完全拮抗劑。Cerlapirdine 具有研究阿爾茨海默病的潛力。