UK 55444 Reaxys ID: 3640038 2-[2-[(2-Amino-4,5-dihydro-4-oxo-1H-imidazol)-1-yl]ethoxymethyl]-4-(2,3-dichlorophenyl)-1,4-dihydro-6-methylpyridine-3,5-dicarboxylic acid 3-ethyl 5-methyl ester
應(yīng)用領(lǐng)域
用途一
UK 55444 is a potent (IC50 = 8 x 10(-9) M) calcium antagonist which is 40-fold selective for vascular over cardiac tissue and which has a significantly longer duration of action (greater than 3 h) than nifedipine in the anesthetized dog on intravenous administration.
