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98353-69-6

英文名稱 troponin I (104-115)
CAS 98353-69-6
分子式 C70H123N27O13
分子量 1550.9
MOL 文件 98353-69-6.mol
98353-69-6 結構式 98353-69-6 結構式

基本信息

英文別名
troponin I (104-115)
Tni peptide (104-115)
Ac-Gly-lys-phe-lys-arg-pro-pro-leu-arg-arg-val-arg-NH2
L-Argininamide, N-acetylglycyl-L-lysyl-L-phenylalanyl-L-lysyl-L-arginyl-L-prolyl-L-prolyl-L-leucyl-L-arginyl-L-arginyl-L-valyl-
(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-acetamidoacetyl)amino]-6-aminohexanoyl]amino]-3-phenylpropanoyl]amino]-6-aminohexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide

應用領域

用途一
Troponin I (104-115) is a cardiac and skeletal muscle protein useful in the laboratory diagnosis of heart attack. It occurs in different plasma concentration but the same circumstances as troponin T - either test can be performed for confirmation of cardiac muscle damage and laboratories usually offer one test or the other._x000D_ Troponin I is a part of the troponin protein complex, where it binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it, myosin cannot bind actin in relaxed muscle. When calcium binds to the troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character.
"98353-69-6" 相關產(chǎn)品信息
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