99290-94-5
99290-94-5 結(jié)構(gòu)式
基本信息
英文別名
Reaxys ID: 5747013(N-piperidinomethyl)-2-chroman
Piperidine, 1-[(3,4-dihydro-2H-1-benzopyran-2-yl)methyl]-
應(yīng)用領(lǐng)域
用途一
The alpha-adrenoceptors blocking effect of (N-piperidinomethyl)-2-chromanne was studied in vivo and in vitro in the rat. In the pithed rat, (N-piperidinomethyl)-2-chromanne (1 mg/kg i.v.) antagonized the pressor effects induced by alpha agonists. (N-piperidinomethyl)-2-chromanne competitively antagonized the pressor effects of M7 (alpha 2-agonist) and cirazoline (alpha 1-agonist). (N-piperidinomethyl)-2-chromanne antagonized the inhibitory effects of clonidine on presynaptic alpha 2-receptors in stimulated pithed rats.