99390-76-8
99390-76-8 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
沸點(diǎn)492.3±45.0 °C(Predicted)
密度1.31±0.1 g/cm3(Predicted)
酸度系數(shù)(pKa)7.85±0.48(Predicted)
應(yīng)用領(lǐng)域
用途一
BMY-27709 is an inhibitor of influenza virus growth. BMY-27709 has an IC50 of 3-8 microM for A/WS33 virus growth in a multicycle replication assay and is active against all H1 and H2 subtype viruses tested. However, BMY-27709 was found to be inactive against H3 subtype viruses, as well as influenza B/Lee/40 virus. BMY-27709 was also found to act against H1 and H2 viruses early in infection, suggesting that the target for inhibition is the hemagglutinin protein.