LEU-PRO-PHE-PHE-ASP
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- CAS號:
- 182912-74-9
- 英文名:
- (PRO18,ASP21)-AMYLOID BETA-PROTEIN (17-21)
- 英文別名:
- IAB5;IAβ5;LPFFD;IA-BETA5;LEU-PRO-PHE-PHE-ASP;H-LEU-PRO-PHE-PHE-ASP-OH;Beta-Sheet Breaker Peptide iAβ5;BETA-SHEET BREAKER PEPTIDE IA-BETA5;[PRO18, ASP21] BETA-AMYLOID (17-21);BETA-SHEET BREAKER PEPTIDE IA-BETA5P
- 中文名:
- LEU-PRO-PHE-PHE-ASP
- 中文別名:
- L-亮氨酰-L-脯氨酰-L-苯丙氨酰-L-苯丙氨酰-L-天冬氨酸;BETA-SHEET BREAKER PEPTIDE IAΒ5 五肽;(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-AMINO-4-METHYLPENTANOYL]PYRROLIDINE-2-CARBONYL]AMINO]-3-PHENYLPROPANOYL]AMINO]-3-PHENYLPROPANOYL]AMINO]BUTANEDIOIC ACID
- CBNumber:
- CB1755202
- 分子式:
- C33H43N5O8
- 分子量:
- 637.72
- MOL File:
- 182912-74-9.mol
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LEU-PRO-PHE-PHE-ASP化學性質(zhì)
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沸點:
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980.0±65.0 °C(Predicted)
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密度:
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1.291±0.06 g/cm3(Predicted)
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儲存條件:
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−20°C
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溶解度:
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≥63.7 mg/mL in DMSO; ≥16.33 mg/mL in EtOH; ≥6.9 mg/mL in H2O with ultrasonic
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形態(tài):
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solid
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酸度系數(shù)(pKa):
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2.88±0.10(Predicted)
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顏色:
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White to off-white
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序列:
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Leu-Pro-Phe-Phe-Asp
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LEU-PRO-PHE-PHE-ASP性質(zhì)、用途與生產(chǎn)工藝
β-Sheet Breaker Peptide iAβ5 是一種有效的腦淀粉樣蛋白-β (Abeta) 降解劑。Abeta 沉積與阿爾茨海默病 (AD) 相關，相關毒性來自于它的 β 折疊構象和聚集。β-Sheet Breaker Peptide iAβ5 可重復誘導體內(nèi)纖維狀淀粉樣沉積物的分解。因此，β-Sheet Breaker Peptide iAβ5 可防止和/或逆轉(zhuǎn)由 Abeta 引起的神經(jīng)元收縮，并減少 Abeta 沉積物周圍白細胞介素 IL-1beta 陽性小膠質(zhì)細胞樣細胞的范圍。β-Sheet Breaker Peptide iAβ5 可減少 AD 中大腦淀粉樣斑塊的大小和/或數(shù)量。β-Sheet Breaker Peptide iAβ5 由疏水性苯甲醇 (HBA) 標簽標記，在酸性條件下呈鮮艷的藍色，可用于定量測定。
LEU-PRO-PHE-PHE-ASP
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
LEU-PRO-PHE-PHE-ASP
生產(chǎn)廠家
LEU-PRO-PHE-PHE-ASP 圖譜信息:
182912-74-9, LEU-PRO-PHE-PHE-ASP 相關搜索:
- β Amyloid Peptides
- Neurodegenerative Disease Peptides
- Amyloid β Protein FragmentsNeuropeptides
- Amyloid beta Protein Fragments
- Alzheimers and Neurodegenerative Disease Research
- peptide
- 目錄多肽
- 目錄肽
- 多肽
- Peptides
- Neurodegenerative Disease Peptides
- Amino Acids and Peptides
- BioChemical
- Amyloid beta Protein Fragments
- Biochemicals and Reagents
- C33H43N5O8
- L-亮氨酰-L-脯氨酰-L-苯丙氨酰-L-苯丙氨酰-L-天冬氨酸
- BETA-SHEET BREAKER PEPTIDE IAΒ5 五肽
- (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-AMINO-4-METHYLPENTANOYL]PYRROLIDINE-2-CARBONYL]AMINO]-3-PHENYLPROPANOYL]AMINO]-3-PHENYLPROPANOYL]AMINO]BUTANEDIOIC ACID
- 182912-74-9
- [Pro18, Asp21] β - Amyloid (17 - 21), iAβ5
- L-Leucyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-L-aspartic acid
- β-Sheet Breaker Peptide iAβ5 (5 mg vial)
- (Pro??,Asp??)-Amyloid β-Protein (17-21)
- (Pro1?,Asp21)-Amyloid β-Protein (17-21) trifluoroacetate salt
- (Pro18,Asp21)-Amyloid β-Protein (17-21)
- (Pro18,Asp21)-Amyloid b-Protein (17-21) trifluoroacetate salt
- (PRO18,ASP21)-AMYLOID BETA-PROTEIN (17-21) USP/EP/BP
- IAβ5
- Beta-Sheet Breaker Peptide iAβ5
- L-Aspartic acid, L-leucyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-
- [PRO18, ASP21] BETA-AMYLOID (17-21)
- [PRO18, ASP21]-AMYLOID B PROTEIN FRAGMENT 17-21 TRIFLUOROACETATE SALT
- [PRO18, ASP21]AMYLOID-BETA PROTEIN (17-21), HUMAN, MOUSE, RAT
- (PRO18,ASP21)-AMYLOID BETA-PROTEIN (17-21)
- [Pro18, Asp21]-AMyloid beta Protein FragMent 17-21 trifluoroacetate salt
- [Pro18, Asp21] beta-Amyloid (17-21), iAb5
- [Pro18, Asp21] β - Amyloid (17 - 21), iAb5
- AMYLOID BETA42 FIBRILLOGENESIS INHIBITOR I
- A-BETA42 FIBRILLOGENESIS INHIBITOR I
- IAB5
- IA-BETA5
- H-LEU-PRO-PHE-PHE-ASP-OH
- LEU-PRO-PHE-PHE-ASP
- [pro18, asp21]-amyloid β protein fragment 17-21 trifluoroacetate salt
- (PRO18,ASP21)AMYLOID BETA PROTEIN*FRAGMENT (17-21)
- BETA-SHEET BREAKER PEPTIDE IA-BETA5
- BETA-SHEET BREAKER PEPTIDE IA-BETA5P
- LPFFD