1-(3-METHOXYBENZYL)-3-(4-(PYRIDIN-4-YL)THIAZOL-2-YL)UREA
|
|
|
- CAS號(hào):
- 1342276-76-9
- 英文名:
- 1-(3-Methoxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea
- 英文別名:
- PKI1313;RKI-1313;PKI 1313;RKI1313;RKI 1313;PKI1313;PKI 1313;RKI1313, 10 mM in DMSO;RKI-1313 (Negative control of RKI-1447);1-(3-Methoxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea;Urea, N-[(3-methoxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl]-;migration,Inhibitor,RKI1313,ROCK substrates,inhibit,ROCK,Rho-associated kinase,Rho-kinase,ROK,anticancer,Rho-associated protein kinase
- 中文名:
- 1-(3-METHOXYBENZYL)-3-(4-(PYRIDIN-4-YL)THIAZOL-2-YL)UREA
- 中文別名:
- 化合物RKI-1313;化合物RKI-1313,10 MM DMSO 溶液;1-(3-甲氧基芐基)-3-[4-(吡啶-4-基)噻唑-2-基]脲
- CBNumber:
- CB22681120
- 分子式:
- C17H16N4O2S
- 分子量:
- 340.4
- MOL File:
- 1342276-76-9.mol
|
|
|
1-(3-METHOXYBENZYL)-3-(4-(PYRIDIN-4-YL)THIAZOL-2-YL)UREA化學(xué)性質(zhì)
-
密度:
-
1.323±0.06 g/cm3(Predicted)
-
|
-
儲(chǔ)存條件:
-
Store at -20°C
-
|
-
溶解度:
-
DMF: 30mg/mL; DMSO: 30mg/mL; DMSO:PBS (pH 7.2) (1:1): 0.5mg/mL
-
|
-
形態(tài):
-
A crystalline solid
-
|
-
酸度系數(shù)(pKa):
-
6.38±0.70(Predicted)
-
|
-
顏色:
-
White to off-white
-
|
1-(3-METHOXYBENZYL)-3-(4-(PYRIDIN-4-YL)THIAZOL-2-YL)UREA性質(zhì)、用途與生產(chǎn)工藝
RKI-1313 是一種 ROCK 抑制劑，對(duì) ROCK 1 和 ROCK 2 的 IC50s 分別為 34、8 μM。RKI-1313 對(duì) ROCK 底物的磷酸化水平、遷移、侵襲或不依賴錨定的生長(zhǎng)顯示較小的影響。
1-(3-METHOXYBENZYL)-3-(4-(PYRIDIN-4-YL)THIAZOL-2-YL)UREA
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS編號(hào) | 包裝 | 價(jià)格 |
|---|
| 2026/06/05 | HY-107209 | RKI-1313 | 1342276-76-9 | 1 mg | 2280元 |
| 2026/06/05 | HY-107209 | 1-(3-METHOXYBENZYL)-3-(4-(PYRIDIN-4-YL)THIAZOL-2-YL)UREA
RKI-1313 | 1342276-76-9 | 5 mg | 5700元 |
1-(3-METHOXYBENZYL)-3-(4-(PYRIDIN-4-YL)THIAZOL-2-YL)UREA
生產(chǎn)廠家
1-(3-METHOXYBENZYL)-3-(4-(PYRIDIN-4-YL)THIAZOL-2-YL)UREA 圖譜信息:
1342276-76-9, 1-(3-METHOXYBENZYL)-3-(4-(PYRIDIN-4-YL)THIAZOL-2-YL)UREA 相關(guān)搜索:
- Inhibitors
- 抑制劑
- 合成材料中間體
- 小分子抑制劑，天然產(chǎn)物
- 小分子抑制劑
- 化合物RKI-1313,10 MM DMSO 溶液
- 化合物RKI-1313
- 1-(3-甲氧基芐基)-3-[4-(吡啶-4-基)噻唑-2-基]脲
- 1342276-76-9
- RKI1313, 10 mM in DMSO
- migration,Inhibitor,RKI1313,ROCK substrates,inhibit,ROCK,Rho-associated kinase,Rho-kinase,ROK,anticancer,Rho-associated protein kinase
- Urea, N-[(3-methoxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl]-
- PKI1313;PKI 1313
- PKI1313
- PKI 1313
- RKI1313;RKI 1313
- RKI-1313 (Negative control of RKI-1447)
- 1-(3-Methoxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea
- RKI-1313