N-[5-(4-氰基苯基)-1H-吡咯并[2,3-B]吡啶-3-基]-3-吡啶甲酰胺
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- CAS號:
- 1093222-27-5
- 英文名:
- N-[5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-3-pyridinecarboxamide
- 英文別名:
- CS-2864;MDK-2275;AKK1-IN-1;Pim1/AKK1-IN-1;3-b]pyridin-3-yl]-;AAK1 dual inhibitor;Pim1/AKK1 inhibitor 1;LKB1(AAK1 dual inhibitor);Pim1/AKK1-IN-1, 10 mM in DMSO;N-[5-(4-cyanophenyl)-1H-pyrrolo[2
- 中文名:
- N-[5-(4-氰基苯基)-1H-吡咯并[2,3-B]吡啶-3-基]-3-吡啶甲酰胺
- 中文別名:
- 化合物PIM1/AKK1-IN-1;PIM1/AKK1/MST2/LKB1抑制劑;化合物PIM1/AKK1-IN-1,10 MM DMSO 溶液;N-(5-(4-氰基苯基)-1H-吡咯并[2,3-b]吡啶-3-基)吡啶-3-甲酰胺;N-[5-(4-氰基苯基)-1H-吡咯并[2,3-B]吡啶-3-基]-3-吡啶甲酰胺;N-[5-(4-氰基苯基)-1H-吡咯并[2,3-B]吡啶-3-基]-3-吡啶甲酰胺N-[5-(4-CYANOPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-3-YL]-3-PYRIDINECARBOXAMIDE
- CBNumber:
- CB32509993
- 分子式:
- C20H13N5O
- 分子量:
- 339.35
- MOL File:
- 1093222-27-5.mol
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N-[5-(4-氰基苯基)-1H-吡咯并[2,3-B]吡啶-3-基]-3-吡啶甲酰胺化學(xué)性質(zhì)
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密度:
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1.42
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儲存條件:
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Store at -20°C
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溶解度:
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insoluble in EtOH; insoluble in H2O; ≥34.8 mg/mL in DMSO
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形態(tài):
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Powder
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酸度系數(shù)(pKa):
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11.62±0.43(Predicted)
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顏色:
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White to gray
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N-[5-(4-氰基苯基)-1H-吡咯并[2,3-B]吡啶-3-基]-3-吡啶甲酰胺性質(zhì)、用途與生產(chǎn)工藝
Pim1/AKK1-IN-1 是一種有效的多種酶抑制劑，能夠作用于 Pim1/AKK1/MST2/LKB1，Kd 值分別為 35 nM/53 nM/75 nM/380 nM。
Kd: 35 nM (Pim1), 53 nM (AKK1), 75 nM (MST2), 380 nM (LKB1)
Pim1/AKK1-IN-1 is multi-kinase inhibitor, and has?K
d
of 380 nM against LKB1 and 53 nM against AAK1.
N-[5-(4-氰基苯基)-1H-吡咯并[2,3-B]吡啶-3-基]-3-吡啶甲酰胺
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS編號 | 包裝 | 價格 |
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| 2026/06/05 | HY-10371 | N-[5-(4-氰基苯基)-1H-吡咯并[2,3-B]吡啶-3-基]-3-吡啶甲酰胺
Pim1/AKK1-IN-1 | 1093222-27-5 | 1 mg | 948元 |
| 2026/06/05 | HY-10371 | N-[5-(4-氰基苯基)-1H-吡咯并[2,3-B]吡啶-3-基]-3-吡啶甲酰胺
Pim1/AKK1-IN-1 | 1093222-27-5 | 5mg | 2130元 |
N-[5-(4-氰基苯基)-1H-吡咯并[2,3-B]吡啶-3-基]-3-吡啶甲酰胺
生產(chǎn)廠家
N-[5-(4-氰基苯基)-1H-吡咯并[2,3-B]吡啶-3-基]-3-吡啶甲酰胺 圖譜信息:
1093222-27-5, N-[5-(4-氰基苯基)-1H-吡咯并[2,3-B]吡啶-3-基]-3-吡啶甲酰胺 相關(guān)搜索:
- 抑制劑
- 對照品
- 細胞生物學(xué)試劑
- N-(5-(4-氰基苯基)-1H-吡咯并[2,3-b]吡啶-3-基)吡啶-3-甲酰胺
- 化合物PIM1/AKK1-IN-1,10 MM DMSO 溶液
- 化合物PIM1/AKK1-IN-1
- PIM1/AKK1/MST2/LKB1抑制劑
- N-[5-(4-氰基苯基)-1H-吡咯并[2,3-B]吡啶-3-基]-3-吡啶甲酰胺N-[5-(4-CYANOPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-3-YL]-3-PYRIDINECARBOXAMIDE
- N-[5-(4-氰基苯基)-1H-吡咯并[2,3-B]吡啶-3-基]-3-吡啶甲酰胺
- 1093222-27-5
- N-(5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)nicotinamide
- Pim1/AKK1-IN-1, 10 mM in DMSO
- Pim kinases,Pim1/AKK1IN1,Pim-1/AKK1-IN-1,inhibit,Pim,Inhibitor,Pim1/AKK1 IN 1
- AKK1-IN-1
- MDK-2275
- AAK1 dual inhibitor
- Pim1/AKK1 inhibitor 1
- N-[5-(4-cyanophenyl)-1H-pyrrolo[2
- LKB1/AAK1 DUAL INHIBITOR;3-PYRIDINECARBOXAMIDE; N-[5-(4-CYANOPHENYL)-1H-PYRROLO[2;3-B]PYRIDIN-3-YL]-
- 3-b]pyridin-3-yl]-
- CS-2864
- LKB1/AAK1 DUAL INHIBITOR;AAK1 DUAL INHIBITOR
- Pim1/AKK1-IN-1
- 3-PyridinecarboxaMide, N-[5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-
- LKB1(AAK1 dual inhibitor)
- N-[5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-3-pyridinecarboxamide