乙基氫化銅蛋白
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- CAS號(hào):
- 3413-58-9
- 英文名:
- ETHYLHYDROCUPREINE HYDROCHLORIDE
- 英文別名:
- neumolisina;OptochineHCl;numoquinhydrochloride;optoquinhydrochloride;optochinhydrochloride;OPTICHIN HYDROCHLORIDE;Ethylhydrocupreine HCI;ETHYLHYDROCUPREINE HYDROCHLORIDE;o-ethyl-hydrocupreinhydrochloride;Ethylhydrocupreine HCl,Optochin HCl
- 中文名:
- 乙基氫化銅蛋白
- 中文別名:
- 奧普托欣;鹽酸奧普托欣;乙基氫化銅蛋白;鹽酸乙基脫甲奎寧;乙氫去甲奎寧鹽酸鹽;鹽酸乙基氫化叩卜林;鹽酸乙基氫化銅色樹(shù)堿;乙基氫化銅色樹(shù)堿鹽酸鹽;乙基氫化脫甲奎寧鹽酸鹽;乙基氫化銅蛋白,97%
- CBNumber:
- CB3434170
- 分子式:
- C21H29ClN2O2
- 分子量:
- 376.92
- MOL File:
- 3413-58-9.mol
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乙基氫化銅蛋白化學(xué)性質(zhì)
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熔點(diǎn):
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121-123°C
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比旋光度:
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D21 -123.6° (water)
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儲(chǔ)存條件:
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2-8°C
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溶解度:
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DMSO : 125 mg/mL (331.64 mM; Need ultrasonic)
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形態(tài):
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Solid
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顏色:
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White to off-white
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敏感性:
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Light Sensitive
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BRN:
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4055970
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主要應(yīng)用:
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forensics and toxicology
pharmaceutical (small molecule)
veterinary-
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InChIKey:
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QNRATNLHPGXHMA-XZHTYLCXSA-N
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SMILES:
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Cl[H].[H][C@@]12CCN(C[C@@H]1CC)[C@@]([H])(C2)[C@H](O)c3ccnc4ccc(OCC)cc34
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乙基氫化銅蛋白性質(zhì)、用途與生產(chǎn)工藝
Ethylhydrocupreine hydrochloride (Optochin hydrochloride) 是一種具有抗菌作用的奎寧衍生物，具有抗肺炎鏈球菌 (S. pneumoniae) 的活性。Ethylhydrocupreine hydrochloride 還具有抗 Plasmodium falciparum 的抗瘧活性，IC50 為 25.75 nM。Ethylhydrocupreine hydrochloride 是一種 Gallus gallus 2 受體 (ggTas2r1，ggTas2r2 和 ggTas2r7) 激動(dòng)劑。
S. pneumoniae
IC50: 25.75 nM (
Plasmodium falciparum
)
ggTas2r1,
ggTas2r2 and ggTas2r7
The mutation rate to Ethylhydrocupreine (Optochin) resistance is estimated using fluctuation analysis in three capsulated
S. pneumoniae
strains (
S. pneumoniae
D39 NCTC 7466,
S. pneumoniae
R6 ATCC BAA-255 and
S. pneumoniae
ATCC 49619). The exposure to subinhibitory concentrations of penicillin increased the mutation rate (expressed as mutation per cell division) to Ethylhydrocupreine (Optochin) resistance between 2.1- and 3.1-fold for all three strains studied.
The injection of 1 cc. of a 24 hour dextrose blood broth culture of virulent Type I pneumococci into the right pleural cavity of guinea pigs produces acute suppurative pleuritis on both sides associated with suppurative pericarditis. The injection of 1 cc. of 1:500 solutions of Ethylhydrocupreine hydrochloride into each pleural cavity of guinea pigs at varying intervals up to 24 hours after pleural infection has usually shown a marked curative influence. Similar results are observed with dogs.
用途
鑒定Streptococcuspneumoniae的特效靈敏試劑。
乙基氫化銅蛋白
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS編號(hào) | 包裝 | 價(jià)格 |
|---|
| 2026/06/05 | HY-136429A | 乙基氫化銅蛋白
Ethylhydrocupreine hydrochloride | 3413-58-9 | 25mg | 304元 |
| 2026/06/05 | HY-136429A | 乙基氫化銅蛋白
Ethylhydrocupreine hydrochloride | 3413-58-9 | 10 mM * 1 mLin DMSO | 334元 |
乙基氫化銅蛋白
生產(chǎn)廠(chǎng)家
3413-58-9, 乙基氫化銅蛋白 相關(guān)搜索:
- Miscellaneous
- 抑制劑
- 乙基氫化銅蛋白
- 醫(yī)藥中間體
- EQ - EZ
- Analytical Standards
- Alphabetic
- Analytical Chromatography Product Catalog
- C21H29ClN2O2
- C21H28N2O2xHCl
- 乙氫去甲奎寧鹽酸鹽,10 MM DMSO 溶液
- CINCHONAN-9-OL,6'-乙氧基-10,11-二氫-,鹽酸鹽(1:1),(8Α,9R)-
- 乙基氫化古銅色堿鹽酸鹽
- 乙基氫化銅色樹(shù)堿鹽酸鹽
- 鹽酸乙基氫化銅色樹(shù)堿
- 乙基氫化銅蛋白
- 乙基氫化脫甲奎寧鹽酸鹽
- 鹽酸乙基脫甲奎寧
- 鹽酸乙基氫化叩卜林
- 鹽酸奧普托欣
- 乙氫去甲奎寧鹽酸鹽
- 乙基氫化銅蛋白,97%
- 奧普托欣
- 乙基氫化銅蛋白,鹽酸奧普托欣
- 3413-58-9
- Ethylhydrocupreine hydrochloride, 10 mM in DMSO
- taste,Ethylhydrocupreine hydrochloride,ggTas2r1,bitter,antimalarial,inhibit,ggTas2r7,Optochin,bactericidal,Antimicrobial,Inhibitor,S. pneumoniae,Parasite,Ethylhydrocupreine,Bacterial,ggTas2r2
- (R)-(6-ethoxyquinolin-4-yl)-[(2S,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]methanol
- Ethylhydrocupreine HCI
- OptochineHCl
- ETHYLHYDROCUPREINE HYDROCHLORIDE*CRYSTAL LINE
- optoquinhydrochloride
- optochinhydrochloride
- o-ethyl-hydrocupreinhydrochloride
- numoquinhydrochloride
- neumolisina
- Ethylhydrocupreine HCl,Optochin HCl
- hydrocupreine,ethylester,hydrochloride
- ETHYLHYDROCUPREINE HYDROCHLORIDE
- OPTICHIN HYDROCHLORIDE