二甲苯氧庚酸-Β-D-葡糖苷酸
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- CAS號:
- 91683-38-4
- 英文名:
- GEMFIBROZIL 1-O--GLUCURONIDE
- 英文別名:
- Gemfibrozil Impurity 12;Gemfibrozil Impurity 13;Gemfibrozilb-D-glucuronide;Gemfibrozil-β-D-glucuronide;Gemfibrozil 1-O-b-Glucuronide;GEMFIBROZIL 1-O-?-GLUCURONIDE;Gemfibrozil 1-O-β-Glucuronide;gemfibrozil 1-O-acylglucuronide;Gemfibrozil-β-O-β-D-Glucuronide;Gemfibrozil b-D-glucuronide ,98%
- 中文名:
- 二甲苯氧庚酸-Β-D-葡糖苷酸
- 中文別名:
- 吉非羅齊雜質12;吉非羅齊雜質10;吉非羅齊雜質13;吉非羅齊1-O葡萄糖醛酸苷;吉非羅齊1-O-Β-葡糖苷酸;吉非貝齊?；?Β-D葡糖苷酸;吉非貝齊 1-O-?；咸擒账?二甲苯氧庚酸-Β-D-葡糖苷酸;二甲苯氧庚酸-Β-D-葡糖苷酸;吉非貝齊酰基-Β-D-葡萄糖苷酸
- CBNumber:
- CB5506729
- 分子式:
- C21H30O9
- 分子量:
- 426.46
- MOL File:
- 91683-38-4.mol
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二甲苯氧庚酸-Β-D-葡糖苷酸化學性質
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熔點:
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>103°C (dec.)
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沸點:
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611.2±55.0 °C(Predicted)
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密度:
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1.32±0.1 g/cm3(Predicted)
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儲存條件:
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Hygroscopic, -20°C Freezer, Under Inert Atmosphere
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溶解度:
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Methanol (Slightly), Water (Slightly)
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酸度系數(shù)(pKa):
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2.68±0.70(Predicted)
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形態(tài):
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Solid
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顏色:
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White to Off-White
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穩(wěn)定性:
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Very Hygroscopic
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二甲苯氧庚酸-Β-D-葡糖苷酸性質、用途與生產(chǎn)工藝
Gemfibrozil 1-O-β-Glucuronide 是 Gemfibrozil (CI-719; HY-B0258) 的代謝產(chǎn)物，是一種有效且競爭性的 P450 (CYP) 亞型 CYP2C8 抑制劑，IC50 為 4.07 μM。
Gemfibrozil 1-O-β-Glucuronide significantly inhibits the OATP2 (OATP1B1)-mediated uptake of Cerivastatin (CER; HY-129458) with an IC
50
of 24.3 μM.
Gemfibrozil 1-O-β-Glucuronide inhibits CYP2C8-mediated M1, M23 formation with IC
50
s of 5.38 μM, 4.30 μM, and has no effects for CYP2C8-mediated M3 formation.
Gemfibrozil 1-O-β-Glucuronide has an IC
50
of 243 μM for the CYP3A4- mediated metabolism.
二甲苯氧庚酸-Β-D-葡糖苷酸
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS編號 | 包裝 | 價格 |
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| 2026/06/05 | HY-129993 | 二甲苯氧庚酸-Β-D-葡糖苷酸
Gemfibrozil 1-O-β-glucuronide | 91683-38-4 | 1 mg | 2800元 |
| 2026/06/05 | HY-129993 | 二甲苯氧庚酸-Β-D-葡糖苷酸
Gemfibrozil 1-O-β-glucuronide | 91683-38-4 | 10 mM * 1 mLin DMSO | 10450元 |
二甲苯氧庚酸-Β-D-葡糖苷酸
生產(chǎn)廠家
91683-38-4, 二甲苯氧庚酸-Β-D-葡糖苷酸 相關搜索:
- Pharmaceuticals
- Metabolites & Impurities
- Intermediates & Fine Chemicals
- Inhibitors
- Glucuronides
- 化學試劑
- 雜質對照品
- 抑制劑
- 二甲苯氧庚酸-Β-D-葡糖苷酸標準品
- 二甲苯氧庚酸-Β-D-葡糖苷酸
- 化合物 GEMFIBROZIL 1-O-Β-GLUCURONIDE
- (2S,3S,4S,5R,6S)-6-((5-(2,5-二甲基苯氧基)-2,2-二甲基戊?；?氧基)-3,4,5-三羥基四氫-2H-吡喃-2-羧酸
- 吉非貝齊酰基-Β-D葡糖苷酸
- 吉非貝齊?；?Β-D-葡萄糖苷酸
- 吉非羅齊1-O-Β-葡糖苷酸
- 吉非羅齊酰基-Β-D-葡萄糖醛酸
- 吉非羅齊雜質12
- 吉非羅齊雜質10
- 吉非羅齊雜質13
- 吉非貝齊 1-O-?；咸擒账?/font>
- 吉非貝齊酰基 - Β-D葡糖苷酸
- 二甲苯氧庚酸-Β-O-Β-D-葡糖苷酸[干冰運輸]
- 吉非羅齊1-O葡萄糖醛酸苷
- 二甲苯氧庚酸-Β-D-葡糖苷酸
- 91683-38-4
- (2S,3S,4S,5R,6S)-6-((5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid?, Gemfibrozil 1-O-β-glucuronide
- GEMFIBROZIL 1-O-GLUCURONIDE/Gemfibrozil 1-O-β-D-glucuronide
- (2S,3S,4S,5R,6S)-6-((5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
- Gemfibrozil acyl-b-D-glucuronide
- Gemfibrozil Impurity 13
- Gemfibrozil-β-O-β-D-Glucuronide D6
- Gemfibrozil 1-O-β-Glucuronide (contains up to 15% α isomer)
DISCONTINUED. Please see G305755.
- Gemfibrozil acyl-β-D-glucuronide
- Gemfibrozil 1-O-β-Glucuronide
- Gemfibrozil Impurity 12
- β-D-Glucopyranuronic acid, 1-[5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate]
- Gemfibrozil-acyl-β-D-glucuronide
- Gemfibrozil-β-O-β-D-Glucuronide
- Gemfibrozil 1-O-β-Glucuronide (contains up to 15% α isomer)
- Gemfibrozil-β-D-glucuronide
- GeMfibrozil Acyl-beta-D-Glucuronide
- Gemfibrozil-acyl-beta-D-glucuronide min. 95%
- Gemfibrozil b-D-glucuronide ,98%
- beta-D-Glucopyranuronic acid, 1-(5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoate)
- 1-o-Gemfibrozil-beta-D-glucuronide
- 1-[5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoate] -D-Glucopyranuroic Acid
- gemfibrozil 1-O-acylglucuronide
- Gemfibrozilb-D-glucuronide
- Gemfibrozil 1-O-b-Glucuronide
- 1-[5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoate] b-D-Glucopyranuroic Acid, Gemfibrozil Glucuronide
- GEMFIBROZIL 1-O-?-GLUCURONIDE