N-(4-丁基-2-甲基苯基)乙酰胺
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- CAS號:
- 143360-00-3
- 英文名:
- N1-(4-BUTYL-2-METHYLPHENYL)ACETAMIDE
- 英文別名:
- CS-1090;SMIP004;SMIP-004;SMIP 004;SMIP 004; SMIP-004;SMIP004, 10 mM in DMSO;4-N-BUTYL-2-METHYLACETANILIDE;4'-(But-1-yl)-2'-methylacetanilide;N-(4-Butyl-2-methylphenyl)acetamide;N1-(4-BUTYL-2-METHYLPHENYL)ACETAMIDE
- 中文名:
- N-(4-丁基-2-甲基苯基)乙酰胺
- 中文別名:
- 化合物SMIP004;N-(4-丁基-2-甲基苯基)乙酰胺;化合物SMIP004,10 MM DMSO 溶液;SMIP004,SKP2 E3 LIGASE 抑制劑
- CBNumber:
- CB6320959
- 分子式:
- C13H19NO
- 分子量:
- 205.3
- MOL File:
- 143360-00-3.mol
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N-(4-丁基-2-甲基苯基)乙酰胺化學(xué)性質(zhì)
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沸點(diǎn):
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343.0±21.0 °C(Predicted)
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密度:
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1.003±0.06 g/cm3(Predicted)
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儲存條件:
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Store at -20°C
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溶解度:
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≥ 20.5 mg/mL in DMSO, ≥ 53.6 mg/mL in EtOH with ultrasonic
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酸度系數(shù)(pKa):
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15.14±0.70(Predicted)
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形態(tài):
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Solid
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顏色:
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White to off-white
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InChI:
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1S/C13H19NO/c1-4-5-6-12-7-8-13(10(2)9-12)14-11(3)15/h7-9H,4-6H2,1-3H3,(H,14,15)
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InChIKey:
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ZFVMECVBUGMWIX-UHFFFAOYSA-N
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SMILES:
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N(c1c(cc(cc1)CCCC)C)C(=O)C
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N-(4-丁基-2-甲基苯基)乙酰胺性質(zhì)、用途與生產(chǎn)工藝
SMIP004 是一種 SKP2 E3 Ligase 抑制劑，下調(diào) SKP2，穩(wěn)定 p27。SMIP004 也是人前列腺癌細(xì)胞選擇性凋亡誘導(dǎo)劑。
SMIP004 decreases the levels of positive cell cycle regulators, upregulates cyclin-dependent kinase inhibitors, and results in G1 arrest, inhibition of colony formation in soft agar, and cell death.
SMIP004 potently inhibits the growth of prostate and breast cancer xenografts in SCID mice.
N-(4-丁基-2-甲基苯基)乙酰胺
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS編號 | 包裝 | 價(jià)格 |
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| 2026/06/05 | HY-15694 | N-(4-丁基-2-甲基苯基)乙酰胺
SMIP004 | 143360-00-3 | 2mg | 922元 |
| 2026/06/05 | HY-15694 | N-(4-丁基-2-甲基苯基)乙酰胺
SMIP004 | 143360-00-3 | 5mg | 1384元 |
N-(4-丁基-2-甲基苯基)乙酰胺
生產(chǎn)廠家
143360-00-3, N-(4-丁基-2-甲基苯基)乙酰胺 相關(guān)搜索:
- 抑制劑
- 細(xì)胞凋亡
- 化合物SMIP004,10 MM DMSO 溶液
- SMIP004,SKP2 E3 LIGASE 抑制劑
- 化合物SMIP004
- N-(4-丁基-2-甲基苯基)乙酰胺
- 143360-00-3
- SKP2 E3 Ligase Inhibitor II, SMIP004
- SMIP004, 10 mM in DMSO
- N-(4-Butyl-2-methylphenyl)acetamide , SMIP004
- E1 activating enzyme,SMIP 004,Inhibitor,Apoptosis,Ubiquitin ligase,E2 conjugating enzyme,Ubiquitin activating enzyme,SMIP004,SMIP-004,inhibit,E3 ligating enzyme,E1/E2/E3 Enzyme,Ubiquitin conjugating enzyme
- Acetamide, N-(4-butyl-2-methylphenyl)-
- CS-1090
- SMIP 004; SMIP-004
- N-(4-Butyl-2-methylphenyl)acetamide
- N-[4-(But-1-yl)-2-methylphenyl]acetamide, 2-Acetamido-5-(but-1-yl)toluene
- 4'-(But-1-yl)-2'-methylacetanilide
- SMIP-004
- SMIP004
- SMIP 004
- 4-N-BUTYL-2-METHYLACETANILIDE
- N1-(4-BUTYL-2-METHYLPHENYL)ACETAMIDE