網(wǎng)站主頁 >> CAS數(shù)據(jù)庫列表 >> N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride
N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride
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- CAS號:
- 864741-95-7
- 英文名:
- N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride
- 英文別名:
- SB 699551 dihydrochloride;SB 699551 dihydrochloride, 5-HT5A receptor antagonist;3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[[4-[4-[(2-phenylethylamino)methyl]phenyl]phenyl]methyl]propanamide;3-Cyclopentyl-N-(2-(dimethylamino)ethyl)-N-((4'-((phenethylamino)methyl)-[1,1'-biphenyl]-4-yl)methyl)propanamide dihydrochloride;3-Cyclopentyl-N-(2-(dimethylamino)ethyl)-N-((4'-((phenethylamino)methyl)-[1,1'-biphenyl]-4-yl)methyl)propanamide dihydrochloride
- 中文名:
- N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride
- 中文別名:
- 化合物 T23325;SB 699551二鹽酸鹽;SB 699551 DIHYDROCHLORIDE,5-HT5A RECEPTOR拮抗劑;3-環(huán)戊基-N-(2-(二甲基氨基)乙基)-N-((4'-((苯乙基氨基)甲基)-[1,1'-聯(lián)苯]-4-基)甲基)丙酰胺二鹽酸鹽
- CBNumber:
- CB82750695
- 分子式:
- C34H46ClN3O
- 分子量:
- 548.21
- MOL File:
- 864741-95-7.mol
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N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride化學性質(zhì)
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儲存條件:
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Inert atmosphere,2-8°C
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溶解度:
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H2O: soluble1mg/mL, clear (warmed)
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形態(tài):
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powder
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顏色:
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white to beige
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水溶解性:
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H2O: 1mg/mL, clear (warmed)
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InChIKey:
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QJMKBIHLMPTYTI-UHFFFAOYSA-N
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SMILES:
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Cl.Cl.N(CCN(Cc2ccc(cc2)c3ccc(cc3)CNCCc4ccccc4)C(=O)CCC1CCCC1)(C)C
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N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride性質(zhì)、用途與生產(chǎn)工藝
SB-699551 是一種有效的選擇性 5-HT5A 拮抗劑，pKi 為 8.3。SB-699551 抑制腫瘤球形成。SB-699551 降低 AKT 絲氨酸殘基 473 (S473)、WNK1、PRAS40 的磷酸化。SB-699551具有抗癌活性，具有乳腺腫瘤研究的潛力。
N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride
生產(chǎn)廠家
N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride 圖譜信息:
864741-95-7, N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride 相關(guān)搜索:
- 抑制劑
- 藥靶配體
- SB 699551 DIHYDROCHLORIDE,5-HT5A RECEPTOR拮抗劑
- SB 699551二鹽酸鹽
- 化合物 T23325
- 3-環(huán)戊基-N-(2-(二甲基氨基)乙基)-N-((4'-((苯乙基氨基)甲基)-[1,1'-聯(lián)苯]-4-基)甲基)丙酰胺二鹽酸鹽
- 864741-95-7
- 3-Cyclopentyl-N-(2-(dimethylamino)ethyl)-N-((4'-((phenethylamino)methyl)-[1,1'-biphenyl]-4-yl)methyl)propanamide dihydrochloride
- SB 699551 dihydrochloride, 5-HT5A receptor antagonist
- 3-Cyclopentyl-N-(2-(dimethylamino)ethyl)-N-((4'-((phenethylamino)methyl)-[1,1'-biphenyl]-4-yl)methyl)propanamide dihydrochloride
- 3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[[4-[4-[(2-phenylethylamino)methyl]phenyl]phenyl]methyl]propanamide
- SB 699551 dihydrochloride