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- CAS號(hào):
- 87100-15-0
- 英文名:
- Cyclohexylboronic acid pinacol ester
- 英文別名:
- 2-Cyclohexyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;1,3,2-Dioxaborolane, 2-cyclohe;Cyclohexane acid pinacol ester;Cyclohexylboronic acid pinacol este;CYCLOHEXYLBORONIC ACID PINACOL ESTER;CYCLOHEXYLBORONIC ACID ACID PINACOL ESTER;REF DUPL: Cyclohexylboronic acid pinacol ester;1,3,2-Dioxaborolane, 2-cyclohexyl-4,4,5,5-tetraMethyl-;2-Cyclohexyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane >(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexane
- 中文名:
- 環(huán)己烷硼酸頻那醇酯
- 中文別名:
- 環(huán)己基硼酸匹那醇酯;環(huán)己基硼酸頻哪醇酯;環(huán)己烷硼酸頻那醇酯;環(huán)乙烷硼酸頻哪醇酯;環(huán)己基硼酸頻呢醇酯;2-環(huán)己基硼酸頻哪醇酯;環(huán)己烷硼酸頻那醇酯 1G;2-環(huán)己基-4,4,5,5-四甲基-1,3,2-二氧環(huán)戊硼烷;2-環(huán)己基-4,4,5,5-四甲基-1,3,2-二氧雜環(huán)戊硼烷;2-CYCLOHEXYL-4錛?錛?錛?-TETRAMETHYL-1錛?錛?-DIOXABOROLANE
- CBNumber:
- CB8491026
- 分子式:
- C12H23BO2
- 分子量:
- 210.12
- MOL File:
- 87100-15-0.mol
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環(huán)己烷硼酸頻那醇酯性質(zhì)、用途與生產(chǎn)工藝
生產(chǎn)方法
以頻哪醇和環(huán)己基硼酸為原料合成2-環(huán)己基-4,4,5,5-四甲基-1,3,2-二氧雜環(huán)戊硼烷的一般步驟如下：將環(huán)己基硼酸（1.0當(dāng)量）、頻哪醇（1.0當(dāng)量）和無水MgSO4（4.0當(dāng)量）在乙醚（Et2O，0.5M）中的混合物于室溫下攪拌16小時(shí)。反應(yīng)完成后，過濾反應(yīng)混合物，并在真空條件下除去溶劑。粗產(chǎn)物通過蒸餾或快速柱色譜法進(jìn)行純化，得到純的2-環(huán)己基-4,4,5,5-四甲基-1,3,2-二氧雜環(huán)戊硼烷。
參考文獻(xiàn)：
[1] Journal of the American Chemical Society, 2012, vol. 134, # 27, p. 11298 - 11298
[2] Synthesis (Germany), 2016, vol. 48, # 19, p. 3241 - 3253
[3] Journal of the American Chemical Society, 2018, vol. 140, # 44, p. 14677 - 14686
[4] Journal of the American Chemical Society, 2017, vol. 139, # 28, p. 9519 - 9522
[5] Synlett, 2018, vol. 29, # 8, p. 1092 - 1094
環(huán)己烷硼酸頻那醇酯
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