替吉莫南
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- CAS號:
- 102507-71-1
- 英文名:
- Tigemonam
- 英文別名:
- Tigemom;SQ-30213;Tigemonam;Antibiotic SQ-30213;[[[(Z)-1-(2-Aminothiazol-4-yl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)azetidin-3-yl]amino]-2-oxoethylidene]amino]oxy]acetic acid;2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-sulfooxyazetidin-3-yl]amino]-2-oxoethylidene]amino]oxyaceticaci;Acetic acid, 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-;Sulfuric acid [(3S)-3-[[2-(2-aminothiazol-4-yl)-2-[(Z)-carboxymethyloxyimino]-1-oxyethyl]amino]-4,4-dimethyl-2-oxoazetidin-1-yl] ester
- 中文名:
- 替吉莫南
- 中文別名:
- 替吉莫南;化合物 T13926
- CBNumber:
- CB91179920
- 分子式:
- C12H15N5O9S2
- 分子量:
- 437.41
- MOL File:
- 102507-71-1.mol
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替吉莫南化學性質(zhì)
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密度:
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1.91±0.1 g/cm3(Predicted)
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儲存條件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系數(shù)(pKa):
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-3+-.0.18(Predicted)
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替吉莫南性質(zhì)、用途與生產(chǎn)工藝
Tigemonam 是一種單菌霉素，可以抵抗革蘭氏陰性需氧細菌病原體。
Tigemonam (0.25 mg/L) inhibits 90% of Escherichia coli, Klebsiella spp., Proteus spp., Salmonella spp., Haemophilus influenzae and Branhamella catarrhalis tested. The MIC
90
for Enterobacter spp. is 16 mg/L and for Citrobacter 4 mg/L. Pseudomonas aeruginosa is resistant to tigemonam but susceptible to aztreonam. Tigemonam shows minimal inoculum dependence, between 10
2
and 10
6
cfu per spot.
Tigemonam shows potent activities against Escherichia coli SC 8294, E. coli SC 12199, Salmonella schottmulleri SC 3850, Proteus mirabilis SC 9575, Providencia rettgeri SC 8217, Klebsiella pneumoniae SC 12216, Serratia marcescens SC 9782, Enterobacter cloacae SC 11078, Haemophilus influenzae SC 10556, with ED
50
of 1.4 mg/kg, 1.5 mg/kg, 0.7 mg/kg, 0.3 mg/kg, 0.2 mg/kg, 0.9 mg/kg, 0.5 mg/kg, 3.9 mg/kg and 1.8 mg/kg in mice.
替吉莫南
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS編號 | 包裝 | 價格 |
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| 2026/06/05 | HY-U00380 | 替吉莫南
Tigemonam | 102507-71-1 | 1 mg | 21792元 |
102507-71-1, 替吉莫南 相關(guān)搜索:
- 抑制劑
- C12H15N5O9S2
- 化合物 T13926
- 替吉莫南
- 102507-71-1
- 2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-sulfooxyazetidin-3-yl]amino]-2-oxoethylidene]amino]oxyaceticaci
- Acetic acid, 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-
- Tigemom
- Sulfuric acid [(3S)-3-[[2-(2-aminothiazol-4-yl)-2-[(Z)-carboxymethyloxyimino]-1-oxyethyl]amino]-4,4-dimethyl-2-oxoazetidin-1-yl] ester
- SQ-30213
- Antibiotic SQ-30213
- [[[(Z)-1-(2-Aminothiazol-4-yl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)azetidin-3-yl]amino]-2-oxoethylidene]amino]oxy]acetic acid
- Tigemonam