偶氮甲烷
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- CAS號:
- 25843-45-2
- 英文名:
- AZOXYMETHANE
- 英文別名:
- AOM;Azoxy;collagen type 2;ANFH;SEDC;STL1;COL11A3;azoxy-methan;AZOXYMETHANE;CH3N=N(→O)CH3
- 中文名:
- 偶氮甲烷
- 中文別名:
- Azoxy;偶氮甲烷;氧化偶氮基甲烷;AOM氧化偶氮甲烷;偶氮甲烷(AOM);偶氨甲烷(AMO);偶氨甲烷(AMO);氧化偶氮甲烷95%;偶氮甲烷[A5486];偶氮甲烷[A5486]
- CBNumber:
- CB9487512
- 分子式:
- C2H6N2O
- 分子量:
- 74.08
- MOL File:
- 25843-45-2.mol
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偶氮甲烷化學(xué)性質(zhì)
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沸點:
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97-99 °C (lit.)
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密度:
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0.991 g/mL at 25 °C (lit.)
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折射率:
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1.4368 (estimate)
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閃點:
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24 °C
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儲存條件:
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-20°C
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溶解度:
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Soluble in water, ethanol, and ether
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形態(tài):
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Liquid
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顏色:
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Oil
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比重:
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0.991
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主要應(yīng)用:
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genomic analysis
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InChI:
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InChI=1S/C2H6N2O/c1-3-4(2)5/h1-2H3
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InChIKey:
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DGAKHGXRMXWHBX-UHFFFAOYSA-N
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SMILES:
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[N+]([O-])(C)=NC
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EPA化學(xué)物質(zhì)信息:
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Azoxymethane (25843-45-2)
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偶氮甲烷性質(zhì)、用途與生產(chǎn)工藝
Azoxymethane 是一種結(jié)腸致癌物質(zhì)，可導(dǎo)致 DNA 加合物的形成。
Azoxymethane is a colon carcinogen which leads to the formation of DNA adducts. On an equal protein basis, hepatic microsomes are much more active than SI and colon microsomes in NADPH-dependent Azoxymethane bioactivation and N
7
-mG adduct formation. Hepatic microsomes show the highest activity in the hydroxylation of Azoxymethane, followed by SI and colon microsomes.
Regardless of the strain, the amounts of O
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-mG and N
7
-mG produced by Azoxymethane are highest in the liver, followed by proximal and distal colons, which have similar levels, and then by duodenum, jejunum and ileum. Results indicate that the Azoxymethane-induced DNA adduct formation in the SI and colon does not depend on bioactivation by hepatic P450 enzymes. Irrespective of the mouse strain, no aberrant crypt foci (ACF) is detected in the colons of saline-treated mice; in contrast, colonic ACF is detected in all three strains of Azoxymethane-treated mice. The Azoxymethane-treated athymic mice have approximately an 11-fold lower tumor incidence than similarly treated WT animals.
類別
有毒物品
毒性分級
高毒
急性毒性
皮下-大鼠 LD50: 27 毫克/公斤
可燃性危險特性
可燃; 燃燒產(chǎn)生有毒氮氧化物煙霧
儲運特性
通風(fēng)低溫干燥; 與庫房食品原料分開存放
滅火劑
干粉,泡沫,沙土,二氧化碳, 霧狀水
偶氮甲烷
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS編號 | 包裝 | 價格 |
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| 2026/06/05 | HY-111375 | 偶氮甲烷
Azoxymethane | 25843-45-2 | 5mg(135mM * 500μL in Water) | 2656元 |
| 2026/06/05 | HY-111375 | 偶氮甲烷
Azoxymethane | 25843-45-2 | 10 mg (135 mM * 1 mL in Water) | 4650元 |
25843-45-2, 偶氮甲烷 相關(guān)搜索:
- 生化試劑
- 抑制劑
- 高端化學(xué)
- 化工原料
- Carcinogens
- Cancer Research
- BioChemical
- CH3NN8594OCH3
- 25843-42-2
- Azoxy
- 氧化偶氮甲烷95%
- 25843-45-2;Azoxymethane 13.4 M, >=98%
- 偶氨甲烷(AMO)
- 結(jié)腸癌造模誘導(dǎo)劑——偶氮甲烷Azoxymethane ,AOM
- 偶氮甲烷[A5486]
- Azoxymethae(AOM)
- 偶氨甲烷(AMO)
- Monoclonal Antibody to COL2A1抗體(別名:AOM
- 偶氮甲烷[A5486]
- 結(jié)腸癌造模誘導(dǎo)劑——偶氮甲烷Azoxymethane ,AOM
- 人Ⅱ型膠原交聯(lián)羧基端肽(CTXⅡ) elisa試劑盒-E-EL-H0837
- 重組人 COL2A1蛋白 (GST,His標(biāo)簽)-PDEH100914
- AZOXYMETHANE 偶氮甲烷(AOM) |CAS 25843-45-2
- PERFEMIKER]氧化偶氮甲烷,95%
- 氧化偶氮基甲烷
- AOM氧化偶氮甲烷
- 偶氮甲烷(AOM)
- 結(jié)腸癌造模誘導(dǎo)劑氧化偶氮甲烷
- 偶氮甲烷
- 25843-45-2
- collagen type 2
- Azoxy
- AOM
- Azoxymethae（AOM）
- Azoxymethane 13.4 M, >=98%
- STL1
- SEDC
- COL11A3
- ANFH
- Alpha-1 type II collagen
- "N,N-Dimethyldiazene N-oxide"
- Azoxymethane
DISCONTINUED
- (Z)-1,2-Dimethyldiazene 1-oxide
- [(E)-methyl-NNO-azoxy]methane
- (E)-dimethyldiazen-1-ium-1-olate
- AZOXYMETHANE
- Methane, azoxy-
- azoxy-methan
- 1,2-Dimethyldiazene 1-oxide
- Diazene, dimethyl-,1-oxide (9CI)
- (Z)-1,2-diMethyldiazene oxide
- CH3N=N(→O)CH3
- ONN-Azoxydimethane
- Dimethyldiazene 1-oxide
- AZOXYMETHANE, PRACTICAL GRADE, 13.4M