Piperazinone, 3-(2-thienyl)- (9CI)
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- CAS-Nr.
- 86696-86-8
- Englisch Name:
- Piperazinone, 3-(2-thienyl)- (9CI)
- Synonyma:
- Tenilsetam;3-(2-thienyl)- (9CI);Tenilsetam/Piperazinone;Tenilsetam, 10 mM in DMSO;3-(2-Thienyl)-2-piperazinone;3-(2-Thienyl)piperazin-2-one;2-Piperazinone, 3-(2-thienyl)-;Piperazinone, 3-(2-thienyl)- (9CI);Tenilsetam - PAS 997 | CAS 997 | HR 029;Piperazinone, 3-(2-thienyl)- (9CI) USP/EP/BP
- CBNumber:
- CB01052655
- Summenformel:
- C8H10N2OS
- Molgewicht:
- 182.24
- MOL-Datei:
- 86696-86-8.mol
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Piperazinone, 3-(2-thienyl)- (9CI) Eigenschaften
- Dichte
- 1.225
- InChI
- InChI=1S/C8H10N2OS/c11-8-7(9-3-4-10-8)6-2-1-5-12-6/h1-2,5,7,9H,3-4H2,(H,10,11)
- InChIKey
- BBACKDMGYMXYLE-UHFFFAOYSA-N
- SMILES
- N1CCNC(C2SC=CC=2)C1=O
Sicherheit
Piperazinone, 3-(2-thienyl)- (9CI) Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Tenilsetam ((+/-)-3-(2-thienyl)-2-piperazinone; Piperazinone, 3-(2-thienyl)- (9CI)), a cognition-enhancing drug successfully used for the treatment of patients suffering from Alzheimer's disease, when included in the Maillard reaction inhibits protein crosslinking by AGEs in vitro. According to the mechanism proposed, Tenilsetam acts via covalent attachment to glycated proteins, thus blocking the reactive sites for further polymerisation reactions. A beneficial effect of Tenilsetam in Alzheimer's disease could come from the interference with AGE-derived crosslinking of amyloid plaques and a decreased inflammatory response by diminished activation of phagocytosing microglia[1].
Piperazinone, 3-(2-thienyl)- (9CI) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Piperazinone, 3-(2-thienyl)- (9CI) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 27)Lieferanten
- Piperazinone, 3-(2-thienyl)- (9CI)
- 3-(2-Thienyl)piperazin-2-one
- 3-(2-Thienyl)-2-piperazinone
- Tenilsetam - PAS 997 | CAS 997 | HR 029
- 2-Piperazinone, 3-(2-thienyl)-
- Piperazinone, 3-(2-thienyl)- (9CI) USP/EP/BP
- 3-(2-thienyl)- (9CI)
- Tenilsetam/Piperazinone
- Tenilsetam, 10 mM in DMSO
- Tenilsetam
- 86696-86-8
- pharmacetical
- PIPERIDINE
