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SMZ/TMP

SMZ/TMP Struktur
8064-90-2
CAS-Nr.
8064-90-2
Englisch Name:
SMZ/TMP
Synonyma:
Trimethoprim-Sulfamethoxazole;TMP-SMX;SMZ/TMP;Septrim;Chemitrim;Trimforte;Trimethoprimsulfa;Co-Trimoxazole (CTX), 95%;Sulfamethoxazole/Trimethoprim;TRIMETHOPRIM/SULPHAMETHOXAZOLE
CBNumber:
CB01105579
Summenformel:
C24H29N7O6S
Molgewicht:
543.6
MOL-Datei:
8064-90-2.mol

SMZ/TMP Eigenschaften

storage temp. 
-20°C
L?slichkeit
DMF: 10mg/mL,DMSO: 10mg/mL,DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL,Ethanol: 0.3mg/mL
Aggregatzustand
liquid
Farbe
colorless to faint yellow
BCS Class
4/4
InChIKey
WZRJTRPJURQBRM-UHFFFAOYSA-N
SMILES
[S](=O)(=O)(Nc4n[o]c(c4)C)c3ccc(cc3)N.Nc1nc(c(cn1)Cc2cc(c(c(c2)OC)OC)OC)N
EPA chemische Informationen
Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-, mixt. with 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine (8064-90-2)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38-43
S-S?tze: 26-36/37
WGK Germany  3
RTECS-Nr. UV8240000
Speicherklasse 12 - Non Combustible Liquids
Hazard Classifications Aquatic Chronic 3
Repr. 2
Giftige Stoffe Daten 8064-90-2(Hazardous Substances Data)
Toxizit?t LD50 orally in mice: 5513 mg/kg (Yamamoto)
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H317 Kann allergische Hautreaktionen verursachen. Sensibilisierung der Haut Kategorie 1A Warnung P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
Sicherheit
P261 Einatmen von Staub vermeiden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

SMZ/TMP Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Cotrimoxazole is an antibiotic. Pseudomonas aeruginosa has a drug resistant rate of 66% in the years 2010-2013.

Weltgesundheitsorganisation (WHO)

The combination of sulfamethoxazole and trimethoprim (5:1) was introduced in 1971 for the treatment of a wide variety of bacterial infections. Its use has been associated with severe sensitivity reactions, many of which have been attributed to the sulphonamide component. Elderly people seem to be more vulnerable. The World Health Organization has no information further to the above concerning restrictive action taken on this combination.

Nebenwirkungen

Trimethoprim/sulfamethoxazole on a daily basis has a rapid onset of action but has rare associated side effects of bone marrow suppression and toxic epidermal necrolysis (TEN).
Nausea, vomiting, and anorexia are generally dose related. Hypersensitivity reactions (including Stevens-Johnson syndrome and hematologic reactions) occur in <5% of patients.

SMZ/TMP Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


SMZ/TMP Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 22)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19853 58
TargetMol Chemicals Inc.
+17819995354
marketing@targetmol.com United States 19956 58
Alfa Chemistry 1-516-6625404
support@alfa-chemistry.com United States 9171 60
Shanghai YuanYe Biotechnology Co., Ltd. 13636370518
shyysw007@163.com China 89686 60
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11218 58
LGC Science (Shanghai) Ltd. 17717235263
fan.yang@LGCgroup.com China 18798 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 11972 58
Huai Hua Binfengchem Co., Ltd 0745-2866851 17711757908
406037272@qq.com China 4383 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 6206333 13167063860
anhua.mao@aladdin-e.com China 49998 58

8064-90-2()Verwandte Suche:


  • SMZ/TMP
  • Sulfamethoxazole/Trimethoprim
  • Trimethoprim-Sulfamethoxazole Combination
  • TRIMETHOPRIM/SULPHAMETHOXAZOLE
  • Chemitrim
  • Septrim
  • Cotrimoxazole, Ready Made Solution
  • TMP-SMX
  • Co-Trimoxazole (CTX), 95%
  • Trimethoprimsulfa
  • Trimforte
  • 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine mixture with 4-amino-N-(5-methyl-3-isoxazolyl)-benzenesulfonamide
  • Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:19)
  • Trimethoprim-Sulfamethoxazole
  • 8064-90-2
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