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Aceperone

Aceperone Struktur
807-31-8
CAS-Nr.
807-31-8
Englisch Name:
Aceperone
Synonyma:
R-3248;Acetabuton;N-[[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-phenylpiperidin-4-yl]methyl]acetamide;N-[[1-[4-(4-fluorophenyl)-4-keto-butyl]-4-phenyl-4-piperidyl]methyl]acetamide;N-[[1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-phenyl-4-piperidinyl]methyl]acetamide;N-[[1-[4-(4-fluorophenyl)-4-oxo-butyl]-4-phenyl-piperidin-4-yl]methyl]ethanamide
CBNumber:
CB01117334
Summenformel:
C24H29FN2O2
Molgewicht:
0
MOL-Datei:
807-31-8.mol

Aceperone Eigenschaften

Schmelzpunkt:
97-100°
CAS Datenbank
807-31-8

Sicherheit

Aceperone Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Aceperone ,ZYF Pharm Chemical

Manufacturing Process

A mixture of 1-benzyl-4-(4-phenyl)-4-(acetaminomethyl)piperidine, 3-(4- fluorobenzoyl)propyl bromide, sodium bicarbonate and anhydrous acetone was stirred and heated under reflux. The resulting mixture was filtered while still hot, and the filtrate was concentrated to dryness under reduced pressure. The residue was washed with ether to give 1-benzyl-1-[3-(4-fiuorobenzoyl)propyl]- (4-phenyl-4-acetaminomethyl)piperidinium bromide.
To a stirred mixture of thiophenol and 15% (W/W) aqueous sodium hydroxide was added the 1-benzyl-1-[3-(4-fluorobenzoyl)propyl]-(4-phenyl-4- acetaminomethyl)piperidinium bromide and the mixture was heated to 85°- 90°C for 2 h. After cooling, solid matter precipitated was collected by filtration and washed with water to give 1-[3-(4-fluorobenzoyl)propyl]-4- (acetaminomethyl)-4-phenylpiperidine, melting point 111°-112°C.

Therapeutic Function

Vasodilator, Antihypertensive, Neuroleptic

Aceperone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Aceperone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • Acetabuton
  • N-[[1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-phenyl-4-piperidinyl]methyl]acetamide
  • R-3248
  • N-[[1-[4-(4-fluorophenyl)-4-keto-butyl]-4-phenyl-4-piperidyl]methyl]acetamide
  • N-[[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-phenylpiperidin-4-yl]methyl]acetamide
  • N-[[1-[4-(4-fluorophenyl)-4-oxo-butyl]-4-phenyl-piperidin-4-yl]methyl]ethanamide
  • 807-31-8
  • C24H29FN2O2
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