Hemopexin
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- CAS-Nr.
- 9013-71-2
- Englisch Name:
- Hemopexin
- Synonyma:
- HPX;Hpxn;Hemopexin;Human Hemopexin;beta-1B-glycoprotein;Human HPX Protein, His Tag;Hemopexin from human plasma
- CBNumber:
- CB01390610
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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Hemopexin Eigenschaften
- storage temp.
- -20°C
- Aggregatzustand
- lyophilized powder
- Biologische Quelle
- human plasma
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
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| HS Code |
3504009000 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
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Hemopexin Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Hemopexin from human plasma has been used
S. aureus surface colonization assay. It has also been used to stimulate mixed lymphocyte cells to determine the biomarkers in acute rejection.
Allgemeine Beschreibung
Hemopexin (HPX) is produced by cells of the central nervous system. It is a 60 kDa serum glycoprotein.
Biochem/physiol Actions
Hemopexin is an acute-phase protein that plays a major protective role against oxidative stress through its heme-scavenging activities. Hemopexin binds heme with high affinity and is critical for recycling the iron bound to heme molecules and for protecting against heme-induced cellular damage. Free heme, when released or lost from proteins like hemoglobin, can catalyze the formation of reactive oxygen species. Heme is lipophilic and interchelates into lipid membranes and participate in the formation of highly-toxic hydroxyl radicals. Hemopexin may also protect against the heme-mediated oxidation of LDL cholesterol. Hemopexin may also serve an anti-inflammatory role via the negative regulation of IL-6 and TNF-α secretion by activated macrophages.
Hemopexin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Hemopexin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 46)Lieferanten
- beta-1B-glycoprotein
- Hemopexin from human plasma
- HPX
- Hpxn
- Hemopexin
- Human Hemopexin
- Human HPX Protein, His Tag
- 9013-71-2
- proteins
