PHENYLPYRAZOLES Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
The phenylpyrazoles form a new class of insecticides discovered in 1987.
Currently only one member of the class, fipronil, has been commercialised.
This class is considered to have a novel mode of action. Studies on
fipronil have shown that it interferes with the passage of chloride ions
through the y-aminobutyric acid (GABA) regulated chloride channel,
thereby disrupting CNS activity. This is also the site of action of the
cyclodiene insecticides, e.g. dieldrin and endosulfan.
There appears to be target site specificity between insects and mammals
with fipronil displaying tighter binding (and thus higher potency) in the
insect GABA chloride channel in comparison with that in vertebrates. Due
to this mode of action, fipronil has proven highly effective in controlling
insects that are resistant to other classes of insecticide.
Fipronil is effective at low dosage rates on many crop types and provides
long-term protection against major lepidopterous and orthopterous
pests on crops and against coleopterous larvae in soil. It is also used in
public health and to control ectoparasites on pets and farm animals. It is
the most recent chemical to be used for locust control and it has been
widely used in a recent outbreak in Madagascar in 1997.
PHENYLPYRAZOLES Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
