(S)-5-IODO-3-[(2-AZETIDINYL)-METHOXY]PYRIDINE Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Colourless oil
Biologische Aktivit?t
A highly potent and subtype-selective agonist for the α 4 β 2 and α 6 β 2 nicotinic acetylcholine receptors. Activates α -CTx-MII-sensitive and -insensitive components of [ 3 H]dopamine release from rat striatal synaptosomes, corresponding to α 6 β 2 and α 4 β 2 (EC 50 values are 12.7 and ~35 nM respectively). ~5000- , 25000- and 140000-fold selective over α 3 β 4, α 7 and muscle nAChR receptors respectively.
(S)-5-IODO-3-[(2-AZETIDINYL)-METHOXY]PYRIDINE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
