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Dexamethasone 21-phosphate disodium salt

Dexamethasone 21-phosphate disodium salt Struktur
2392-39-4
CAS-Nr.
2392-39-4
Englisch Name:
Dexamethasone 21-phosphate disodium salt
Synonyma:
decadronphosphate;DEXAMETHASON SODIUM PHOSPHATE;DEXAMETHASONE PHOSPHATE SODIUM;Dexamethasone sodium phosphate for peak identification;1,4-PREGNADIEN-9-ALPHA-FLUORO-16-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 21-PHOSPHATE, DISODIUM SALT;Ak-Dex;Baldex;Decdan;dexagro;Dexagel
CBNumber:
CB0153737
Summenformel:
C22H28FNa2O8P
Molgewicht:
516.4
MOL-Datei:
2392-39-4.mol

Dexamethasone 21-phosphate disodium salt Eigenschaften

Schmelzpunkt:
233-235 °C
alpha 
D +57° (water); D25 +74 ±4° (calcd on water-free and alcohol-free basis, concn of 10 mg/ml): USP XIX, p 124
storage temp. 
2-8°C
L?slichkeit
H2O: 50 mg/mL, clear, faintly yellow
Aggregatzustand
White Powder
Farbe
white to off-white
PH
pH(10g/l, 25℃) : 7.5~10.5
Wasserl?slichkeit
Soluble in water. Slightly soluble in ethanol. Insoluble in dichloromethane.
Merck 
13,2960
BRN 
6473066
Stabilit?t:
Hygroscopic
InChIKey
PLCQGRYPOISRTQ-FCJDYXGNSA-L
SMILES
[C@@]12([H])C[C@@H](C)[C@](O)(C(=O)COP([O-])([O-])=O)[C@@]1(C)C[C@H](O)[C@]1(F)[C@@]3(C)C=CC(=O)C=C3CC[C@@]21[H].[Na+].[Na+] |&1:0,3,5,15,18,20,22,32,r|
CAS Datenbank
2392-39-4(CAS DataBase Reference)
EPA chemische Informationen
Dexamethasone disodium phosphate (2392-39-4)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 22-40-63
S-S?tze: 36/37/39
WGK Germany  3
RTECS-Nr. TU4056000
3-10
TSCA  TSCA listed
HS Code  2937220000
Speicherklasse 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Repr. 2
Bildanzeige (GHS) Exclamation Mark (GHS07)Health Hazard (GHS08)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.

Dexamethasone 21-phosphate disodium salt Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R22:Gesundheitssch?dlich beim Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.
R63:Kann das Kind im Mutterleib m?glicherweise sch?digen.

S-S?tze Betriebsanweisung:

S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Chemische Eigenschaften

White or almost white, very hygroscopic powder.

Verwenden

Dexamethasone 21-phosphate disodium salt acts as an inducer of apoptosis and inhibitor of the sodium phosphate symporter. It is used in the treatment of emetic effects of cancer therapy and epicondylitis. Further, it serves as an activator of food, medicine, glucocorticoid and anti inflammatory.

Definition

ChEBI: An organic sodium salt which is the disodium salt of dexamethasone phosphate.

Sicherheitsprofil

Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. Human systemic effects by intravenous route: peritonitis, central nervous system, and gastrointestinal changes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of F-, PO,, and Na2O.

Dexamethasone 21-phosphate disodium salt Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Dexamethasone 21-phosphate disodium salt Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 597)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
APOLLO HEALTHCARE RESOURCES
+6596580999
sales@apollo-healthcare.com.sg Singapore 399 58
CHONGQING CHENCHENG PHARMACEUTICAL CO.,LTD.
15923947264
lf19823605252@163.com China 121 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055
Sibel@chuanghaibio.com China 8738 58
shandong perfect biotechnology co.ltd
+86-53169958659 +86-13153181156
sales@sdperfect.com China 294 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 20122 58
Hebei Kangcang new material Technology Co., LTD
+8615713292910
Nancy@kangcang.com.cn China 341 58
Watson Biotechnology Co.,Ltd
+86-18186686046 +86-18186686046;
sales01@watsonbiotech.cn China 5733 58
Shaanxi Xianhe Biotech Co., Ltd
+86-17709210191; +8617709210191
Jerry@xhobio.com China 906 58
Wuhan JiyunZen Tech Co., Ltd.
+86-18062099985
Amyjiyunzen@yeah.net China 672 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21587 55

2392-39-4()Verwandte Suche:


  • dexadreson
  • dexagro
  • dexamethasonedisodiumphosphate
  • disodiumdexamethasonephosphate
  • disodiumsalt,(11beta,16alpha)-y)
  • DEXAMETHASONE 21-PHOSPHATE DISODIUM SALT
  • DEXAMETHASONE PHOSPHATE DISODIUM SALT
  • dexamethasone 21-(disodium phosphate)
  • DEXAMETHASONE SODIM PHOSPHATE
  • Dexamethasone acetate phosphate
  • DEXAMETHASONE 21-PHOSPHATE DISODIUM
  • DEXAMETHASONE SODIUM PHOSPHATE BP STANDARD(CRM STANDARD)
  • DEXAMETHASONE SODIUM PHOSPHATE BP(CRM STANDARD)
  • DEXAMETHASONE SODIUM PHOSPHATE EPD(CRM STANDARD)
  • DEXAMETHASONE SODIUM PHOSPHATE MM(CRM STANDARD)
  • DEXAMETHASONE SODIUM PHOSPHATE WHO(CRM STANDARD)
  • DexamethasoneSodiumPhosphateBp
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11.beta.,16.alpha.)-
  • DEXAMETHASONESODIUMPHOSPHATE,POWDER,USP
  • Ak-Dex
  • Baldex
  • Colvasone
  • Corson (pharmaceutical)
  • Dalalone
  • Decdan
  • Dexabene
  • Dexagel
  • Dexamethasone phosphate sodium salt
  • Dexamethazone sodium phosphate
  • Disodium dexamethasone 21-monophosphate
  • Disodium dexamethasone 21-phosphate
  • Maxidex Ointment
  • Orgadrone
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11β,16α)-
  • Dexamethasone 21-Phosphate Disodium Salt Hydrate
  • Dexamethasone Sodium Phosphate (350 mg)
  • Dexamethasone 21-phosphate disodium salt, >=98%
  • 9-FLUORO-11 BETA,17 ALPHA,21-TRIHYDROXY-16 ALPHA-METHYLPREGNA-1,4-DIENE-3,20-DIONE-21-(DIHYDROGENPHOSPHATE)DIS
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-(dihydrogen phosphate) disodium salt
  • 21-Phosphate disodium salt
  • megacort
  • pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonoox
  • sodiumdexamethasonephosphate
  • soldesam
  • solu-decadron
  • spersadox
  • 9α-Fluoro-16α-methyl-3,20-dioxo-1,4-pregnadiene-11β,17α,21-triol 21-(phosphoric acid disodium) salt
  • Phosphoric acid 9α-fluoro-11β,17α-dihydroxy-16α-methyl-3,20-dioxo-1,4-pregnadien-21-yldisodium salt
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-(dihydrogen phosphate) disodium salt (8CI)
  • Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-phosphate disodium salt (6CI)
  • Solu-Deca
  • 9-Fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione disodium salt
  • disodium [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
  • disodium [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] phosphate
  • disodium [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-3-keto-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] phosphate
  • Dexamethasone Sodium Phosphate USP (powder)
  • DexaMethasone 21-phosphate disodiu
  • DexaMethasone SodiuM Phosphate USP
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