2'',3'',5''-Triacetyl -azacytidine
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- CAS-Nr.
- 10302-78-0
- Englisch Name:
- 2'',3'',5''-Triacetyl -azacytidine
- Synonyma:
- 2',3',5'-triacetyl-5-Azacytidine;Nsc291930;-O-triacetate;Triacetyl azacitidine;Azacitidine Triacetate;Azacitidine Impurity 48;Intermediate of Azacitidine;2'3'5'-triacetyl-5-Azacytosine;2',3',5'-Tri-O-Acetyl-Azacytidine;2'',3'',5''-Triacetyl -azacytidine
- CBNumber:
- CB01564248
- Summenformel:
- C14H18N4O8
- Molgewicht:
- 370.32
- MOL-Datei:
- 10302-78-0.mol
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2'',3'',5''-Triacetyl -azacytidine Eigenschaften
- Siedepunkt:
- 497.3±55.0 °C(Predicted)
- Dichte
- 1.60±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- L?slichkeit
- ≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
- Aggregatzustand
- crystalline solid
- pka
- 3.06±0.20(Predicted)
- Aussehen
- White to off-white Solid
- InChI
- InChI=1/C14H18N4O8/c1-6(19)23-4-9-10(24-7(2)20)11(25-8(3)21)12(26-9)18-5-16-13(15)17-14(18)22/h5,9-12H,4H2,1-3H3,(H2,15,17,22)/t9-,10-,11-,12-/s3
- InChIKey
- OTQJVHISAFFLMA-IOCWGDCUNA-N
- SMILES
- [C@H]1(O[C@@H]([C@@H](OC(C)=O)[C@H]1OC(=O)C)COC(C)=O)N1C(=O)N=C(N)N=C1 |&1:0,2,3,8,r|
- CAS Datenbank
- 10302-78-0
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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2'',3'',5''-Triacetyl -azacytidine Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
5-
Azacytidine is an inhibitor of DNA methyltransferase, potentially serving to reverse epigenetic changes. It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes and cancer. 2’,3’,5’-
triacetyl-
5-
Azacytidine is a prodrug form of 5-
azacytidine that may be rapidly absorbed orally without formation of major metabolites in the gastrointestinal tract.
Chemische Eigenschaften
White to off-white powder
Verwenden
5-Azacytidine is an inhibitor of DNA methyltransferaes, potentially serving to reverse epigenetic changes. It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes and cancer. 2’,3’,5’-triacetyl-5-Azacytidine is a prodrug form of 5-azacytidine that may be rapidly absorbed orally without formation of major metabolites in the gastrointestinal tract.[Cayman Chemical]
2'',3'',5''-Triacetyl -azacytidine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2'',3'',5''-Triacetyl -azacytidine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 129)Lieferanten
10302-78-0()Verwandte Suche:
- 2'',3'',5''-Triacetyl -azacytidine
- 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-o-acetyl-.beta.-D-ribofuranosyl)-
- Nsc291930
- S-Triazin-2(1H)-one, 4-amino-1-.beta.-D-ribofuranosyl-, triacetate (ester)
- 1,3,5-Triazin-2(1H)-one, 4-aMino-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-
- (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate
- Intermediate of Azacitidine
- 2'3'5'-triacetyl-5-Azacytosine
- 2',3',5'-Tri-O-Acetyl-Azacytidine
- Azacitidine Triacetate
- Triacetyl azacitidine
- 2,3,5-tri-O-acetyl-β-D-ribofuranose-4-amino-1,3,5-triazine
- 1,3,5-Triazin-2(1H)-one, 4-amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-
- -O-triacetate
- 4-Amino-1-(2,3,5-tri-o-acetyl-beta-d-ribofuranosyl)-1,3,5-triazin-2(1h)-one
- 5-Azacytidine 2’,3’5’-O-triacetate
- Azacitidine Impurity 48
- 2'',3'',5''-Triacetyl -azacytidine
- 2',3',5'-Tri-O-acetyl-5-azacytidine
- triethylenetetramine-N,N,N',N'',N'''
- 2'',3'',5''-triacetyl-5-Azacytidine
- 2'',3'',5''-triacetyl-5-Azacytidine, 10 mM in DMSO
- 2′,3′,5′-Triacetyl-azacytidine, CAS 10302-78-0
- 2',3',5'-Tri-O-acetyl-5-azacytidine
- 2',3',5'-triacetyl-5-Azacytidine
- 10302-78-0
