2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate
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- CAS-Nr.
- 1001067-09-9
- Englisch Name:
- 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate
- Synonyma:
- Teoc-NT;2-(TRIMETHYLSILYL)ETHYL 3-NITRO-1,2,4-TRIAZOLE-1-CARBOXYLATE;3-Nitro-1-[2-(trimethylsilyl)ethoxycarbonyl]-1H-1,2,4-triazole;2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate;2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate;3-Nitro-1H-1,2,4-triazole-1-carboxylic Acid 2-(Trimethylsilyl)ethyl Ester;1H-1,2,4-Triazole-1-carboxylic acid, 3-nitro-, 2-(trimethylsilyl)ethyl ester;3-Nitro-1H-1,2,4-triazole-1-carboxylic Acid 2-(Trimethylsilyl)ethyl Ester
3-Nitro-1-[2-(trimethylsilyl)ethoxycarbonyl]-1H-1,2,4-triazole
Teoc-NT
- CBNumber:
- CB01570298
- Summenformel:
- C8H14N4O4Si
- Molgewicht:
- 258.31
- MOL-Datei:
- 1001067-09-9.mol
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2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate Eigenschaften
- storage temp.
- Storage temp. 2-8°C
- L?slichkeit
- Sol organics (CH2Cl2, THF, CH3CN, EtOAc); reacts with amines.
- Aggregatzustand
- powder to crystal
- Farbe
- White to Light yellow
- InChI
- InChI=1S/C8H14N4O4Si/c1-17(2,3)5-4-16-8(13)11-6-9-7(10-11)12(14)15/h6H,4-5H2,1-3H3
- InChIKey
- BHTJYIDOVYPNKR-UHFFFAOYSA-N
- SMILES
- N1(C(OCC[Si](C)(C)C)=O)C=NC([N+]([O-])=O)=N1
- CAS Datenbank
- 1001067-09-9
Sicherheit
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate Chemische Eigenschaften,Einsatz,Produktion Methoden
Physikalische Eigenschaften
Mp (dec.) 85–86 °C.
Verwenden
2-(Trimethylsilyl)ethoxycarbonyl
(Teoc) group is one of the most useful protecting groups for amines, which can be cleaved by fluoride ion under neutral conditions. However, 2-(trimethylsilyl)ethyl chloroformate(Teoc-Cl), which is generally used for the introduction of the Teoc protecting group in amines, is quite unstable and easy to decompose; therefore, distillation is recommended at regular
intervals. On the other hand, Teoc-NT is a highly stable, nonhygroscopic crystalline material and can be stored for long periods without decomposition. Generally, carbamate formation proceeds quickly under neutral conditions, and highly pure carbamates are obtained without tedious column chromatographic
purification. Furthermore, the coproduct 3-nitro-1,2,4-triazole (NT) can be recycled. It participates in the reactions of Reactions with Amines and Aminoalcohols, Amine Protection for Nucleosides, Reaction with Alcohols, etc.
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 40)Lieferanten
1001067-09-9()Verwandte Suche:
- 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate
- 3-Nitro-1-[2-(trimethylsilyl)ethoxycarbonyl]-1H-1,2,4-triazole
- 3-Nitro-1H-1,2,4-triazole-1-carboxylic Acid 2-(Trimethylsilyl)ethyl Ester
- 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate
- 3-Nitro-1H-1,2,4-triazole-1-carboxylic Acid 2-(Trimethylsilyl)ethyl Ester
3-Nitro-1-[2-(trimethylsilyl)ethoxycarbonyl]-1H-1,2,4-triazole
Teoc-NT
- 2-(TRIMETHYLSILYL)ETHYL 3-NITRO-1,2,4-TRIAZOLE-1-CARBOXYLATE
- 1H-1,2,4-Triazole-1-carboxylic acid, 3-nitro-, 2-(trimethylsilyl)ethyl ester
- Teoc-NT
- 1001067-09-9
- C8H14N4O4Si
- Protection & Derivatization Reagents (for Synthesis)
- Synthetic Organic Chemistry
