(R)-1-(2,4-Dichlorophenyl)ethanamine
|
|
|
- CAS-Nr.
- 133773-29-2
- Englisch Name:
- (R)-1-(2,4-Dichlorophenyl)ethanamine
- Synonyma:
- EOS-60919;(R)-1-(2,4-chlorophenyl)ethanaMine;(R)-1-(2,4-DICHLOROPHENYL)ETHANAMINE;(1R)-1-(2,4-dichlorophenyl)ethylamine;(R)-1-(2,4-dichlorophenyl)ethan-1-amine;(1R)-1-(2,4-DICHLOROPHENYL)ETHAN-1-AMINE;Benzenemethanamine, 2,4-dichloro-α-methyl-, (αR)-;(1R)-1-(2,4-Dichlorophenyl)ethanamine Hydrochloride
- CBNumber:
- CB0168881
- Summenformel:
- C8H9Cl2N
- Molgewicht:
- 190.07
- MOL-Datei:
- Mol file
|
(R)-1-(2,4-Dichlorophenyl)ethanamine Eigenschaften
- Siedepunkt:
- 256.4±25.0 °C(Predicted)
- Dichte
- 1.262±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 8.28±0.10(Predicted)
- Aggregatzustand
- liquid
- Farbe
- Colourless
- Optische Rotation
- 37.568°(C=0.01g/ml ETOH)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung
|
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
|
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
|
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
|
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
|
|
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
|
(R)-1-(2,4-Dichlorophenyl)ethanamine Chemische Eigenschaften,Einsatz,Produktion Methoden
Synthese
(5)-Mandelic acid (40.2 g, 264.5 mmol) was added to a solution of 3:2 isopropyl alcohol (/PrOH) and ethanol (EtOH) (500 mL) at room temperature, and the suspension was heated at 60 °C until a clear solution formed. Racemic 2,4-dichloro-a-methyl benzylamine (50 g, 264.5 mmol) was added to the hot solution, which was then cooled to 30 °C over 2 h and stirred at this temperature for 24 h. The colorless crystals were collected by filtration and washed with acetone (70 mL). The resulting salt was suspended in 3:2 /PrOH/EtOH (400 mL) at room temperature and the mixture was heated at 60 °C to give a clear solution. The solution was then cooled to room temperature and stirred for 24 hours. The colorless crystals were filtered off, and washed with acetone (40 mL) to give the desired salt. A portion of the salt (12.0 g) in dichloromethane (CH2C12) (100 mL) was added to aqueous 4 N sodium hydroxide solution (30 mL). The reaction mixture was stirred for 1 h at room temperature, and extracted with dichloromethane (2 χ 100 mL), dried with anhydrous sodium sulfate (Na2S04), filtered, and concentrated in vacuo to afford (R)-1-(2,4-Dichlorophenyl)ethanamine as a colorless liquid (7.5 g, 39.5 mmol, 40%).
(R)-1-(2,4-Dichlorophenyl)ethanamine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(R)-1-(2,4-Dichlorophenyl)ethanamine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 73)Lieferanten
- (R)-1-(2,4-DICHLOROPHENYL)ETHANAMINE
- (1R)-1-(2,4-DICHLOROPHENYL)ETHAN-1-AMINE
- (R)-1-(2,4-chlorophenyl)ethanaMine
- (R)-1-(2,4-dichlorophenyl)ethan-1-amine
- (1R)-1-(2,4-Dichlorophenyl)ethanamine Hydrochloride
- (1R)-1-(2,4-dichlorophenyl)ethylamine
- Benzenemethanamine, 2,4-dichloro-α-methyl-, (αR)-
- EOS-60919
- 133773-29-2
