14,15-LEUKOTRIENE C4 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway. 14,15-LTC₄ is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-LOs on arachidonic acid via 15-HpETE and 14,15-LTA₄ intermediates. 14,15-LTC₄ is classified as an eoxin, because it is formed mostly by eosinophils. However, mast cells and nasal polyps can synthesize 14,15-LTC₄ as well. Little is known about the physiological actions of 14,15-LTC₄. It has weak contractile activity on both guinea pig ileum and pulmonary parenchyma in contrast to the effects of 5-LO-derived LTs. However, in an in vitro permeability assay, 14,15-LTC₄ can increase vascular permeability of human endothelial cell monolayers, with similar potency to that of 5-LO-derived LTs resulting in plasma leakage - a hallmark of inflammation.

Verwenden

14,15-Leukotriene C4 is an acute inflammatory mediator.

14,15-LEUKOTRIENE C4 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

14,15-LEUKOTRIENE C4 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9804	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44918	58
Shanghai Yiyan Biotechnology Co. , Ltd.	021-69985186 13611928337	3427709316@qq.com	China	7982	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29867	58
Cayman Chemical Company	--	sales@caymanchem.com	China	6838	58
Enzo Biochem Inc	--	Enzoname@qq.com	China	6174	58
Santa Cruz Biotechnology Inc	--	scbt@scbt.com	China	6594	58

75290-60-7()Verwandte Suche:

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• 14,15-LEUKOTRIENE C4
• 14,15-LTC4
• EOXIN C4
• EXC4
• Glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-13-carboxy-1-[(1S)-1-hydroxyhexyl]-2,4,6,9-tridecatetraen-1-yl]-L-cysteinyl-
• OBQVBASHEWLKCQ-PKBWNXTMSA-N
• 75290-60-7