(1-Hydroxyethyliden)bis-phosphons?ure, Dinatrium-Salz
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- CAS-Nr.
- 7414-83-7
- Bezeichnung:
- (1-Hydroxyethyliden)bis-phosphons?ure, Dinatrium-Salz
- Englisch Name:
- Etidronate disodium
- Synonyma:
- ETIDRONATE;DisodiuM Etidronate Hydrate;Etidron;sm-5600;Calcimux;Didronel;didronelr;BA 49280E;Sodium etidronate;sodiumethidronate
- CBNumber:
- CB0207300
- Summenformel:
- C2H9NaO7P2
- Molgewicht:
- 230.02
- MOL-Datei:
- 7414-83-7.mol
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(1-Hydroxyethyliden)bis-phosphons?ure, Dinatrium-Salz Eigenschaften
- Schmelzpunkt:
- >300 °C
- storage temp.
- 15-25°C
- L?slichkeit
- H2O: 26 mg/mL
- Aggregatzustand
- solid
- Farbe
- white
- Wasserl?slichkeit
- Soluble in water (26 mg/ml).
- Merck
- 14,3863
- Stabilit?t:
- Hygroscopic
- Kosmetik-Inhaltsstoffe Funktionen
- CHELATING
- Erinnerung an die inhaltsstoffe
- Etidronate disodium (7414-83-7)
- InChI
- InChI=1S/C2H8O7P2.Na.H/c1-2(3,10(4,5)6)11(7,8)9;;/h3H,1H3,(H2,4,5,6)(H2,7,8,9);;
- InChIKey
- MFKOTRZLMIUIGE-UHFFFAOYSA-N
- SMILES
- C(O)(C)(P(O)(O)=O)P(O)(O)=O.[NaH]
- CAS Datenbank
- 7414-83-7
- EPA chemische Informationen
- Phosphonic acid, (1-hydroxyethylidene)bis-, disodium salt (7414-83-7)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| S-S?tze: |
36/37/39 |
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| WGK Germany |
1 |
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| RTECS-Nr. |
SZ8562240 |
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| TSCA |
TSCA listed |
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| HS Code |
29319090 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Acute Tox. 4 Oral |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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(1-Hydroxyethyliden)bis-phosphons?ure, Dinatrium-Salz Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
Beschreibung
Agents in the first generation (e.g., etidronate disodium and tiludronate) that were dosed continuously
produced poorly mineralized bone, because there was no interval for appropriate bone mineralization to
occur. Subsequent studies that used a cyclic dosing schedule (400 mg/day for 2 weeks, followed by 2.5 months
of calcium supplementation only) showed improvement in bone mineralization. Etidronate has been
approved for treatment of Paget's disease of the bone but not for treatment of osteoporosis. Tiludronate
is approximately 10-fold more potent than etidronate and, when given orally for 6 months (200, 400, or 800
mg/day), increases BMD by 2%. No further bone loss was detected in patients 6 months after cessation of
therapy.
Chemische Eigenschaften
White Crystalline Solid
Verwenden
Etidronate disodium is a bisphosphonate antiresorptive agent,it is used as a calcium regulator.
Definition
ChEBI: An organic sodium salt resulting from the replacement of two protons from etidronic acid (one from from each of the phosphonic acid groups) by sodium ions.
Sicherheitsprofil
Poison by intravenous
and subcutaneous routes. Moderately toxic
by ingestion. An experimental teratogen.
Other experimental reproductive effects.
When heated to decomposition it emits
toxic fumes of POx, and Na2O.
(1-Hydroxyethyliden)bis-phosphons?ure, Dinatrium-Salz Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(1-Hydroxyethyliden)bis-phosphons?ure, Dinatrium-Salz Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 417)Lieferanten
7414-83-7((1-Hydroxyethyliden)bis-phosphons?ure, Dinatrium-Salz)Verwandte Suche:
- Sodium etidronate
- didronelr
- disodium(1-hydroxyethylidene)diphosphonate
- disodium1-hydroxyethylidenephosphonate
- disodiumdihydrogen(1-hydroxyethylidene)diphosphonate
- disodiumethanol-1,1-diphosphonate
- disodiumethydronate
- 1-Hydroxyethylidone-1,1-diphosphonicaciddisodiumsalt
- 1-Hydroxyethylidone-1,1-diphosphonicacidpentasodiumsalt
- Pentasodiumetidronate
- 1-Hydroxyethylidone-1,1-diphosphonicacid
- 1-Hydroxyethylidone-1,1-diphosphonicacidtrisodiumsalt
- Calcimux
- Etidron
- DIPHOSPHONICACID,(1-HYDROXYETHYLENE)-,DISODIUMSALT
- DIPHOSPHONICACID,(1-HYDROXYETHYLIDENE)-,DISODIUMSALT
- etidronate disodium，ETD
- Dinatriumdihydrogen(1-hydroxyethyliden)bisphosphonat
- 1-Hydroxyethylidene-1,1-bis-(phosphonic acid) disodium salt
- Phosphonicacid, P,P'-(1-hydroxyethylidene)bis-, sodiuM salt (1:2)
- DisodiuM of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid (HEDPNa2)
- Etidronate Disodium (200 mg)
- (1-Hydroxyethane-1,1-diyl)diphosphonic acid disodi
- Didronel
- disodium hydroxy-[1-hydroxy-1-[hydroxy(oxidanidyl)phosphoryl]ethyl]phosphinate
- disodium hydroxy-[1-hydroxy-1-[hydroxy(oxido)phosphoryl]ethyl]phosphinate
- 1-Hydroxyethane-1,1-diphosphonic Acid DisodiuM Salt
- BA 49280E
- DisodiuM (1-Hydroxyethylidene)-1,1-bisphosphonate
- P,P'-(1-Hydroxyethylidene)bisphosphonic Acid SodiuM Salt
- Disodium 1-Hydroxyethane-1,1-diphosphonate
1-Hydroxyethane-1,1-diphosphonic Acid Disodium Salt
Etidronic Acid Disodium Salt
- Etidronate disodiuM hydrate
- DIHYDROGEN (1-HYDROXYETHYLIDENE)BISPHOSPHONATE DISODIUM
- DISODIUM ETIDRONATE
- hedp disodium salt
- ETIDRONATE DISODIUM
- Etidronic acid disodium salt
- ETRIDRONIC ACID, DISODIUM SALT
- 1-HYDROXYETHYLIDENE-1,1-DIPHOSPHONIC ACID DISODIUM SALT
- (1-HYDROXYETHYLIDENE)BISPHONIC ACID
- (1-HYDROXYETHYLIDENE)BISPHOSPHONIC ACID
- (1-hydroxyethane-1,1-diyl)diphosphonicaciddisodiumsalt
- (1-hydroxyethane-1,1-diyl)di-phosphonicacidisodiumsalt
- (1-hydroxyethylidene)bis-phosphonicacidisodiumsalt
- (1-hydroxyethylidene)diphosphonicacid,disodiumsalt
- (1-hydroxyethylidene)di-phosphonicacidisodiumsalt
- ethane-1-hydroxy-1,1-diphosphonicacid,disodiumsalt
- Phosphonicacid,(1-hydroxyethylidene)bis-,disodiumsalt
- sm-5600
- sodiumethidronate
- sodiumethydronate
- ethydronate disodium
- ETIDRONATE DISODIUM (1-HYDROXYETHYLIDONE-1,1-DIPHOSPHONIC ACID DISODIUM SALT)
- ETIDRONATE DISODIUM USP(CRM STANDARD)
- Dihydrogen (1-hydroxyethylidene)bisphosphonate disodium hydrate
- disodium dihydrogen (1-hydroxyethylidene)bisphosphonate
- Etidronate (sodium salt)
- Etidronate disodium hydrate, 98%, protein tyrosine phosphatase inhibitor
