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enniatin A

enniatin A Struktur
2503-13-1
CAS-Nr.
2503-13-1
Englisch Name:
enniatin A
Synonyma:
enniatin A;Lateritin I;N-Methylcyclo(L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-);(3S,6R,9S,12R,15S,18R)-3,9,15-tris[(2S)-butan-2-yl]-4,10,16-trimethyl-6,12,18-tri(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;Cyclo[(2R)- 2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl- N-methyl-L- isoleucyl]
CBNumber:
CB02079105
Summenformel:
C36H63N3O9
Molgewicht:
681.906
MOL-Datei:
2503-13-1.mol

enniatin A Eigenschaften

Schmelzpunkt:
122-124 °C
Siedepunkt:
847.4±65.0 °C(Predicted)
Dichte
1.022±0.06 g/cm3(Predicted)
storage temp. 
-20°C
L?slichkeit
DMSO: soluble10mg/mL
Aggregatzustand
White to off-white crystalline solid.
pka
-0.96±0.70(Predicted)
Biologische Quelle
Gnomonia errabunda
InChIKey
TWHBYJSVDCWICV-BHZTXFQCSA-N
SMILES
N1([C@H](C(=O)O[C@@H](C(=O)N([C@H](C(=O)O[C@@H](C(=O)N([C@H](C(=O)O[C@@H](C1=O)C(C)C)[C@H](CC)C)C)C(C)C)[C@H](CC)C)C)C(C)C)[C@H](CC)C)C

Sicherheit

Kennzeichnung gef?hrlicher T
R-S?tze: 23/24/25
S-S?tze: 45
RIDADR  2811
WGK Germany  3
HazardClass  6.1(a)
PackingGroup  I
HS Code  2934999090
Speicherklasse 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral

enniatin A Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Enniatins are cyclohexadepsipeptides commonly isolated from fungi that are known to have antibiotic properties and to induce apoptosis in several cancer lines. Many function as ionophores, forming pores in cellular membranes to allow selective ion transport. Enniatin A is one of four major analogs in the enniatin complex . It has been shown to moderately inhibit acyl-CoA:cholesterol acyltranferase activity in rat liver microsomes with an IC50 value of 22 μM. Enniatin A also demonstrates anthelmintic properties against N. brasiliensis, T. spiralis, and H. spumosa.

Verwenden

Enniatins are a family of depsipeptide ionophores, produced by several Fusarium species. More recently, the effects of the enniatins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumour action have received more focus. Enniatin A is one of four major analogues of the enniatin complex and has not previously been available for investigation.

Definition

ChEBI: An enniatin obtained from formal cyclocondensation of three N-[(2R)-2-hydroxy-3-methylbutanoyl]-N-methyl-L-isoleucine units.

enniatin A Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


enniatin A Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 68)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 33024 60
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19936 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30224 58
TargetMol Chemicals Inc.
+1-781-999-5354;
support@targetmol.com United States 39037 58
Aladdin Scientific

tp@aladdinsci.com United States 52923 58
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51395 80
ShangHai Angti Biotechnology Co., Ltd. 13764913901
info@angtibio.com China 4975 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9804 58
Qingdao IniKem BioPharmaTech Co.,Ltd 0532-58268781 18561687109
sales@inikem.com China 300 55

2503-13-1()Verwandte Suche:


  • enniatin A
  • N-Methylcyclo(L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-N-methyl-L-Ile-D-Hmb-)
  • Lateritin I
  • Cyclo[(2R)- 2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl- N-methyl-L- isoleucyl]
  • (3S,6R,9S,12R,15S,18R)-3,9,15-tris[(2S)-butan-2-yl]-4,10,16-trimethyl-6,12,18-tri(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone
  • 2503-13-1
  • C36H63N3O9
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