Ciprofloxacin hydrochloride
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- CAS-Nr.
- 93107-08-5
- Englisch Name:
- Ciprofloxacin hydrochloride
- Synonyma:
- CIPROFLOXACIN HCL;CIPROFLOXACIN HYDROCHLORIDE;1-Cyclopropyl-6-fluoro;1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride;Cyproxan;BAY-o-9867;Bay-09867 (hydrochloride);Clprofloxacin hydrochloride;Ciprofloxacin hydrochloride
- CBNumber:
- CB02130396
- Summenformel:
- C17H18FN3O3.HCl
- Molgewicht:
- 367.8
- MOL-Datei:
- 93107-08-5.mol
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Ciprofloxacin hydrochloride Eigenschaften
- Schmelzpunkt:
- >300 ºC
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- insoluble in EtOH; ≥33.87 mg/mL in H2O; ≥9.34 mg/mL in DMSO with ultrasonic
- Aggregatzustand
- crystalline solid
- Farbe
- White to off-white
- BCS Class
- 3
- InChI
- InChI=1S/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;/h7-10,19H,1-6H2,(H,23,24);1H
- InChIKey
- DIOIOSKKIYDRIQ-UHFFFAOYSA-N
- SMILES
- O=C(O)C1C(=O)C2=CC(=C(C=C2N(C2CC2)C=1)N1CCNCC1)F.[H]Cl
- CAS Datenbank
- 93107-08-5
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
24/25 |
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| HS Code |
29339900 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Ciprofloxacin hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-bacterial
Trademarks
Ciloxan (Alcon); Cipro (Bayer); Proquin (Esprit).
Synthese
The preparation method of ciprofloxacin HCl, its step is as follows:
a) cyclopropyl carboxylic acid is added in the organic solvent, and the adding piperazine, reacted 3～8 hours down as acid binding agent with alkali at 60～120 ℃, the monitoring cyclopropyl carboxylic acid is residual less than 2% o'clock termination reaction, stirring is cooled to 0～30 ℃, leaves standstill suction filtration;
b) add water and hydrochloric acid in the products therefrom toward a) step, under agitation be warming up to molten clearly, add activated carbon decolorizing, filtered while hot, and transfer filtrate pH to 2～4 with hydrochloric acid, and the cooling crystallization filters, rinsing, and drying makes ciprofloxacin HCl.
Ciprofloxacin hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Ciprofloxacin hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 389)Lieferanten
93107-08-5()Verwandte Suche:
- 3-Quinolinecarboxylicacid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-,hydrochloride (1:1)
- BAY-o-9867
- Cyproxan
- 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid monohydrochloride
- 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, monohydrochloride
- Clprofloxacin hydrochloride
- 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride
- Ciprofloxacin hydrochloride CAS 93107-08-5
- Bay-09867 (hydrochloride)
- Enrofloxacin EP Impurity BQ: What is
Enrofloxacin EP Impurity B Q: What is the CAS Number of
Enrofloxacin EP Impurity B
- 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride
- 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
- CIPROFLOXACIN HYDROCHLORIDE
- 1-Cyclopropyl-6-fluoro
- Bay-09867 (hydrochloride)|||Ciprofloxacin HCl|||Ciprofloxacin hydrochloride
- Ciprofloxacin-HCl in Methanol
- C11668500 Ciprofloxacin hydrochloride
- Ciprofloxacin hydrochloride
- Ciprofloxacin (CPX) hydrochloride
- Ciprofloxacin hydrochloride RS
- Ciprofloxacin monohydrochloride (Standard)
- CIPROFLOXACIN HCL
- 93107-08-5
- C17H19ClFN3O3xHCl
- Pharmaceutical intermediate
- 93107-08-5
