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PAC-1-d8

PAC-1-d8 Struktur
1287241-26-2
CAS-Nr.
1287241-26-2
Englisch Name:
PAC-1-d8
Synonyma:
PAC-1-d8;[2H8]-PAC-1;YQNRVGJCPCNMKT-SRNXAORYSA-N
CBNumber:
CB02511333
Summenformel:
C23H28N4O2
Molgewicht:
392.49402
MOL-Datei:
1287241-26-2.mol

PAC-1-d8 Eigenschaften

L?slichkeit
soluble in DMSO, Methanol
Aggregatzustand
Solid
Farbe
Off-White

Sicherheit

PAC-1-d8 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Labelled PAC-1 is a caspase 3 activator. Caspase activation is a key strategy in cancer therapy. Caspase 3 is a key executioner caspase and direct effector of apoptosis. Hallmark of many cancers is the circumvention of signal in the activation of executioner caspases and loss of apoptotic response. EC50 for caspase 3 activation = 0.33 μM and caspase 7= 4.5 μM. The IC50 for apoptosis induction = 0.92 μM. Elevated caspase 3 level in cancerous cell lines and tissues allows PAC-1 to selectively induce apoptosis in tissues.

PAC-1-d8 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


PAC-1-d8 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 16)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
J & K SCIENTIFIC LTD. 18210857532; 18210857532
jkinfo@jkchemical.com China 96815 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32321 50
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979
info@tsbiochem.com China 8065 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
sales@rrkchem.com China 57422 58
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44909 58
Biosynth Biological Technology (Suzhou) Co Ltd --
sales@biosynth.com China 6051 58
Santa Cruz Biotechnology Inc --
scbt@scbt.com China 6594 58

  • PAC-1-d8
  • YQNRVGJCPCNMKT-SRNXAORYSA-N
  • [2H8]-PAC-1
  • 1287241-26-2
  • C23H20D8N4O2
  • Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Pharmaceuticals
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