HYPERFORIN
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- CAS-Nr.
- 11079-53-1
- Englisch Name:
- HYPERFORIN
- Synonyma:
- HYPERFORIN;HYPERFORIN MIX;HYPERFORIN MIX(P);HYPERFORIN USP/EP/BP;Hyperforin (solution in Ethanol);Hyperforin - solution in methanol;Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-;Hyperforin dicyclohexylammonium salt, active constituent of St. John#39s wort;methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-,(1R,5S,6R,7S)-;4-HYDROXY-6R-METHYL-1R,3,7S-TRIS(3-METHYL-2-BUTENYL)-5S-(2-METHYL-1-OXOPROPYL)-6R-(4-METHYL-3-PENTENYL)-BICYCLO[3.3.1]NON-3-ENE-2,9-DIONE
- CBNumber:
- CB0273398
- Summenformel:
- C35H52O4
- Molgewicht:
- 536.78
- MOL-Datei:
- 11079-53-1.mol
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HYPERFORIN Eigenschaften
- Schmelzpunkt:
- 79-80℃
- alpha
- D18 +41° (in ethanol)
- Siedepunkt:
- 616.8±55.0 °C(Predicted)
- Dichte
- 1.010±0.06 g/cm3 (20 ºC 760 Torr)
- Flammpunkt:
- 9℃
- storage temp.
- -20°C
- Aggregatzustand
- solution
- pka
- 4.8 (50% aq ethanol)
- InChIKey
- IWBJJCOKGLUQIZ-HQKKAZOISA-N
- SMILES
- CC(C)C(=O)[C@@]12C(O)=C(C\C=C(\C)C)C(=O)[C@@](C\C=C(/C)C)(C[C@H](C\C=C(\C)C)[C@@]1(C)CC\C=C(\C)C)C2=O
- CAS Datenbank
- 11079-53-1
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
  
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H225 |
Flüssigkeit und Dampf leicht entzündbar. |
Entzündbare Flüssigkeiten |
Kategorie 2 |
Achtung |
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P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501 |
| H370 |
Sch?digt die Organe. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 1 |
Achtung |
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P260, P264, P270, P307+P311, P321,P405, P501 |
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| Sicherheit |
| P210 |
Von Hitze, hei?en Oberfl?chen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
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HYPERFORIN Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
St. John’s wort is a widely consumed herbal preparation which has been claimed to have a number of medicinal properties. It contains a number of known lipid signalling mediators, including chlorogenic acid, hypericin, hyperforin, and I3,II8-biapigenin. Hyperforin exhibits two activities which may alter the action of other concurrent medications. It inhibits the activity of several CYP450 enzymes, with CYP2D6 being the most sensitive with an IC50 of about 10 μg/ml. Hyperforin is also a ligand for the steroid X receptor (SXR). Since one activity of this receptor is the induction of CYP450 expression, the exact nature of hyperforin’s drug-drug interactions must be evaluated on a case-by-case basis. However, these interactions certainly complicate its use as a human therapeutic.[Cayman Chemical]
Definition
ChEBI: A cyclic terpene ketone that is a prenylated carbobicyclic acylphloroglucinol derivative produced by St. John's Wort, Hypericum perforatum.
Allgemeine Beschreibung
Hyperforin is a phloroglucinol component of St. John′s wort and a pregnane X receptor ligand.
HYPERFORIN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
HYPERFORIN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 104)Lieferanten
11079-53-1()Verwandte Suche:
- Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-
- methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-,(1R,5S,6R,7S)-
- 4-HYDROXY-6R-METHYL-1R,3,7S-TRIS(3-METHYL-2-BUTENYL)-5S-(2-METHYL-1-OXOPROPYL)-6R-(4-METHYL-3-PENTENYL)-BICYCLO[3.3.1]NON-3-ENE-2,9-DIONE
- HYPERFORIN
- (1R,5S)-4-Hydroxy-6-methyl-1,3,7β-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6α-(4-methyl-3-pentenyl)bicyclo[3.3.1]non-3-ene-2,9-dione
- HYPERFORIN MIX(P)
- Hyperforin (solution in Ethanol)
- Bicyclo[3.3.1]non-3-ene-2,9-dione,4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-,(1R,5S,6R,7S)-
- HYPERFORIN USP/EP/BP
- HYPERFORIN MIX
- Hyperforin dicyclohexylammonium salt, active constituent of St. John#39s wort
- Hyperforin - solution in methanol
- 11079-53-1
- C35H52O4
- BioChemical
- Anti-Proliferative Agents
- Antitumor Agents
- Cancer Research
- AntidepressantsNutrition Research
- Anti-Proliferative AgentsNeurobiology
- Antitumor Agents
- Biochemicals Found in Plants
- Cancer Research
- Isoprenoid/terpenoid
- Pharmacologicals
- Miscellaneous Natural Products
