Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2

689284-12-6

CAS-Nr.: 689284-12-6

Englisch Name:: Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2

Synonyma:: TAPI-2 acetate salt;Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2;N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-t-butyl-glycine-L-alanine 2-aminoethyl amide;N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide;L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-

CBNumber:: CB02750664

Summenformel:: C19H37N5O5

Molgewicht:: 415.53

MOL-Datei:: 689284-12-6.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 13

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Eigenschaften

storage temp.: -20°C

Aggregatzustand: lyophilized solid

Farbe: white to off-white

InChIKey: LMUSZKBIFGOFBD-RAFLFFCLSA-N

SMILES: CC(O)=O.CC(C)C[C@H](CC(=O)NO)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)NCCN)C(C)(C)C

Sicherheit

WGK Germany	3
Speicherklasse	11 - Combustible Solids

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

TAPI 2 is a matrix metalloprotease (MMP) inhibitor, which inhibits merpin α and β homo-oligomers.

Biochem/physiol Actions

TAPI-2 is a potent inhibitor matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase). It blocks the shedding of several cell surface proteins such as β-amyloid precursor protein, inhibits TNF-α release as well as a diverse variety of membrane-anchored cytokines, cell adhesion molecules, receptors, ligands. TAPI-2 is considered a fairly broad metalloproteinase inhibitor, but it much more selective for TACE than GM6001.

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 13)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7751	56
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51395	80
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24957	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	6000	58
Huai Hua Binfengchem Co., Ltd	0745-2866851 17711757908	406037272@qq.com	China	4385	58
R&D Systems, Inc	--	rdname@qq.com	China	6960	58
Enzo Biochem Inc	--	Enzoname@qq.com	China	6174	58
Merck KGaA	--	ordercn@merckgroup.com	China	6394	58

N-(R)-(2-(Hydroxyaminocarbonyl)methyl)-4-methylpentanoyl-L-t-butyl-glycine-L-alanine 2-aminoethyl amide
TAPI-2 acetate salt
Tumor necrosis factor-α protease inhibitor-2, TNF-α protease inhibitor-2
N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide
L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-
689284-12-6

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