diethyl 4-oxo-4H-pyran-2,5-dicarboxylate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

4-Oxo-4H-pyran-2,5-dicarboxylic Acid 2,5-Diethyl Ester is an intermediate used in the synthesis of Defluoro Dolutegravir (D228715), which is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

diethyl 4-oxo-4H-pyran-2,5-dicarboxylate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

diethyl 4-oxo-4H-pyran-2,5-dicarboxylate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
Alchemist-pharm chemical Technology Co. Ltd.	0371-67991738 13783628208	carl@alchemist-pharm.com	China	1872	58
Shandong Shenganbei New Energy Co. , Ltd. . Nanjing branch	18761883648	sab202211@163.com	China	1668	58

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• diethyl 4-oxo-4H-pyran-2,5-dicarboxylate
• diethyl isochelidonate
• 4H-Pyran-2,5-dicarboxylic acid, 4-oxo-, 2,5-diethyl ester
• 1246616-74-9