9-PAHSA
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- CAS-Nr.
- 1481636-31-0
- Englisch Name:
- 9-PAHSA
- Synonyma:
- 9-PAHSA;MHQWHZLXDBVXML-UHFFFAOYSA-N;9-[(1-oxohexadecyl)oxy]-octadecanoicacid;Octadecanoic acid, 9-[(1-oxohexadecyl)oxy]-
- CBNumber:
- CB03152528
- Summenformel:
- C34H66O4
- Molgewicht:
- 538.89
- MOL-Datei:
- 1481636-31-0.mol
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9-PAHSA Eigenschaften
- Siedepunkt:
- 619.2±38.0 °C(Predicted)
- Dichte
- 0.916±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- L?slichkeit
- DMF: 20 mg/ml; DMSO: 15 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
- pka
- 4.78±0.10(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to off-white
- InChI
- 1S/C34H66O4/c1-3-5-7-9-11-12-13-14-15-16-18-23-27-31-34(37)38-32(28-24-20-17-10-8-6-4-2)29-25-21-19-22-26-30-33(35)36/h32H,3-31H2,1-2H3,(H,35,36)
- InChIKey
- MHQWHZLXDBVXML-UHFFFAOYSA-N
- SMILES
- CCCCCCCCCC(OC(CCCCCCCCCCCCCCC)=O)CCCCCCCC(O)=O
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
WGK 3 |
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| Hazard Classifications |
Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 3
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 1
STOT SE 3 |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H331 |
Giftig bei Einatmen. |
Akute Toxizit?t inhalativ |
Kategorie 3 |
Achtung |
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P261, P271, P304+P340, P311, P321,P403+P233, P405, P501 |
| H336 |
Kann Schl?frigkeit und Benommenheit verursachen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Schl?frigkeit und Benommenheit) |
Warnung |
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P261, P271, P304+P340, P312,P403+P233, P405, P501 |
| H351 |
Kann vermutlich Krebs verursachen. |
Karzinogenit?t |
Kategorie 2 |
Warnung |
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P201, P202, P281, P308+P313, P405,P501 |
| H372 |
Sch?digt bei Hautkontakt und Verschlucken die Organe bei l?ngerer oder wiederholter Exposition. |
Spezifische Zielorgan-Toxizit?t (wiederholte Exposition) |
Kategorie 1 |
Achtung |
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P260, P264, P270, P314, P501 |
| H412 |
Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gew?ssergef?hrdend |
Kategorie 3 |
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P273, P501 |
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| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
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9-PAHSA Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-
fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (
e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to a hydroxylated C-16 or C-18 lipid. 9-PAHSA is a FAHFA in which palmitic acid is esterified to 9-hydroxy stearic acid. PAHSAs are the most abundant forms of FAHFA in serum as well as white and brown adipose tissues of glucose tolerant AG4OX mice, which overexpress Glut4 specifically in adipose tissue. 9-PAHSA is the predominant isomer of PAHSA in wild type and AG4OX mice. It is found in humans and is reduced in the serum and adipose tissues of insulin-
resistant humans. 9-PAHSA improves glucose tolerance, stimulates insulin secretion, and has anti-
inflammatory effects in mice.
Verwenden
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to a hydroxylated C-16 or C-18 lipid. 9-PAHSA is a FAHFA in which palmitic acid is esterified to 9-hydroxy stearic acid. PAHSAs are the most abundant forms of FAHFA in serum as well as white and brown adipose tissues of glucose tolerant AG4OX mice, which overexpress Glut4 specifically in adipose tissue. 9-PAHSA is the predominant isomer of PAHSA in wild type and AG4OX mice. It is found in humans and is reduced in the serum and adipose tissues of insulin-resistant humans. 9-PAHSA improves glucose tolerance, stimulates insulin secretion, and has anti-inflammatory effects in mice.[Cayman Chemical]
Allgemeine Beschreibung
9-(Palmitoyloxy)octadecanoic acid (9-PAHSA) is a palmitic acid ester of 9-hydroxystearic acid.
9-PAHSA Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
9-PAHSA Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 36)Lieferanten
- 9-PAHSA
- MHQWHZLXDBVXML-UHFFFAOYSA-N
- Octadecanoic acid, 9-[(1-oxohexadecyl)oxy]-
- 9-[(1-oxohexadecyl)oxy]-octadecanoicacid
- 1481636-31-0
