Pirinixic Acid Aminothiazole Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LO) are key enzymes in the synthesis of PGE2 and leukotrienes (LTs), respectively. PGE2 and LTs are bioactive lipids that contribute to a broad range of pathologies, including inflammation and various forms of cancer. Pirinixic acid aminothiazole is a dual inhibitor of mPGES-1 and 5-LO (IC50s = 0.4 and 0.2 μM, respectively). It is a weak inhibitor of COX-1 and -2 and has no effect on 12- and 15-LO isoforms. Pirinixic acid aminothiazole reduces the synthesis of PGE2 and LTC4 during zymosan-induced peritonitis in mice, resulting in a significantly diminished inflammatory response.[Cayman Chemical]

Pirinixic Acid Aminothiazole Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Pirinixic Acid Aminothiazole Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
Shanghai Beckham Medical Technology Co., Ltd	13816613772	huahero21@sina.com	China	2826	55
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11972	58
Cayman Chemical Company	--	sales@caymanchem.com	China	6838	58
ApexBio Technology	--	sales@apexbt.com	United States	6251	58
Guangzhou Qingyan Biotechnology Co., Ltd.	--		CHINA	6470	58
Guangzhou Ruifeng Biotechnology Co., Ltd.	--		CHINA	6980	58
Guangzhou Squirrel Biotechnology Co., Ltd.	--		CHINA	6609	58

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• Pirinixic Acid Aminothiazole
• Pirinixic Acid Aminothiazole Exclusive
• BADFIDKPYNKNRT-UHFFFAOYSA-N
• Octanoic acid, 2-[[4-chloro-6-[[4-(2-naphthalenyl)-2-thiazolyl]amino]-2-pyrimidinyl]thio]-
• 5-LOmPGES1-IN-1
• 1492060-44-2