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2',3,4',5,7-Pentahydroxyflavon

MORIN Struktur
480-16-0
CAS-Nr.
480-16-0
Bezeichnung:
2',3,4',5,7-Pentahydroxyflavon
Englisch Name:
MORIN
Synonyma:
2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chroMen-4-one;MONOUNDECANOIN;2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-Benzopyran-4-one;2-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4h-1-benzopyran-4-on;MORIN;FUSTIC;CI 75660;al-morin;Morin-RM;boisd’arc
CBNumber:
CB0316037
Summenformel:
C15H10O7
Molgewicht:
302.24
MOL-Datei:
480-16-0.mol

2',3,4',5,7-Pentahydroxyflavon Eigenschaften

Schmelzpunkt:
299-300 °C (dec.)(lit.)
Siedepunkt:
363.28°C (rough estimate)
Dichte
1.3616 (rough estimate)
Brechungsindex
1.4790 (estimate)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
L?slichkeit
methanol: 50 mg/mL
Aggregatzustand
powder
Colour Index 
75660
pka
6.30±0.40(Predicted)
Farbe
yellow
Wasserl?slichkeit
0.25g/L(20 ºC)
Merck 
6269
Stabilit?t:
Stable. Incompatible with strong oxidizing agents.
InChI
1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H
InChIKey
YXOLAZRVSSWPPT-UHFFFAOYSA-N
SMILES
O=C1C(O)=C(C(C(O)=C2)=CC=C2O)OC3=CC(O)=CC(O)=C31
LogP
1.27-1.54 at 37℃ and pH7.4
CAS Datenbank
480-16-0(CAS DataBase Reference)
EPA chemische Informationen
Morin (480-16-0)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi,T
R-S?tze: 36/37/38-25
S-S?tze: 26-36-45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
RTECS-Nr. LK8749000
8-10-23
TSCA  TSCA listed
HS Code  29329990
Speicherklasse 11 - Combustible Solids
Hazard Classifications Aquatic Chronic 2
Toxizit?t LD50 intraperitoneal in mouse: 555mg/kg
Bildanzeige (GHS) Skull and Crossbones (GHS06)
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizit?t oral Kategorie 3 Achtung P264, P270, P301+P310, P321, P330,P405, P501
Sicherheit
P301+P310 BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

2',3,4',5,7-Pentahydroxyflavon Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

yellow to brown powder

Verwenden

Morin is a natural pentahydroxyflavonol with antioxidant activity. It reduces CD36 expression and oxLDL uptake in U937-derived macrophages, inhibits PIM-1 kinase in vitro (IC50 = 2.7 μM), and reduces the activity of cytochrome P450 isoform 3A4 in liver microsomes. Through these and other actions, morin has anti-oxidant, anti-inflammatory, and other actions in animal models.[Cayman Chemical]

Definition

ChEBI: A pentahydroxyflavone that is 7-hydroxyflavonol bearing three additional hydroxy substituents at positions 2' 4' and 5.

Sicherheitsprofil

Moderately toxic by intraperitoneal route. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

l?uterung methode

Stir morin at room temperature with ten times its weight of absolute EtOH, then leave overnight to settle. Filter it off, and evaporate under a heat lamp to one-tenth its volume. An equal volume of water is added, and the precipitated morin is filtered off, dissolved in the minimum amount of EtOH and again precipitated with an equal volume of water. The precipitate is filtered off, washed with water and dried at 110o for 1hour (yield ca 2.5%.). [Perkins & Kalkwarf Anal Chem 28 1989 1956.] It complexes with W and Zr. [Beilstein 18 H 239, 18 III/IV 3468, 18/5 V 492.]

2',3,4',5,7-Pentahydroxyflavon Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2',3,4',5,7-Pentahydroxyflavon Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 378)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shandong Xuhuang New material CoLTD
+86-15095020839 +86-17660422208
China 726 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21587 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
Chengdu Greenpure Biopharma CO.,Ltd
18283602253; +8618283602253
jancyzheng@gcgreenpure.com China 954 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29815 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897
sales@biopurify.com China 4616 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49979 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780
sale@simagchem.com China 17346 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879
sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58

480-16-0(2',3,4',5,7-Pentahydroxyflavon)Verwandte Suche:


  • TIMTEC-BB SBB008853
  • MORIN
  • FUSTIC
  • CI 75660
  • CI NO 75660
  • 3,5,7,2',4'-PENTAHYDROXYFLAVONE
  • 2',3,4',5,7-PENTAHYDROXYFLAVONE
  • 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4h-1-benzopyran-4-on
  • MORIN, REAG
  • MORIN (2',3,4',5,7-pentahydroxyflavone)
  • Morus alba L
  • 2’,3,4’,5,7-pentahydroxy-flavon
  • 2’,4’,3,5,7-pentahydroxyflavone
  • 2’-hydroxypelargidenolon1522
  • 3,5,7,2’,4’-pentahydroxyflavonol
  • abcolfustic
  • Morin anhydrous
  • 2-(2,4-Dihydroxyphenyl)
  • -3,5,7-trihydroxy-4H-chromen-4-one
  • al-morin
  • boisd’arc
  • zlutprirodni11
  • MorinGr-(2'3,4',5,7-Pentahydroxyflavone)
  • 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-
  • 35746PENTAHYDROXYFLAVONEDIHYDRATE
  • MORIN WITH HPLC
  • MORIN extrapure AR
  • C.I.Natural Yellow 8
  • Morin,98%
  • 3,5,7-Trihydroxy-2-(2,4-dihydroxyphenyl)-4H-chromen-4-one
  • Calico Yellow
  • Toxylon pomiferum
  • Morin Hydrate (AluminiumIonophore I, C.I. 75660) extrapure AR, 98%
  • Morin, 98%, from bark of Moraceae
  • MONOUNDECANOIN
  • Morin transfer
  • Mulberry pigment
  • 3-hydroxy-5-(6-hydroxy-7,7-dimethyl-6,7-dihydro-5H-furo[3,2-g]chromen-2-yl)phenyl beta-D-xylopyranoside
  • Morin(SH)
  • Morin-RM
  • 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzenebenzopyran-4-one
  • Morin (Standard)
  • 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-Benzopyran-4-one
  • 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chroMen-4-one
  • 2-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4h-1-benzopyran-4-on
  • 480-16-0
  • C15H10O7
  • Flavonoids
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Biochemistry
  • Flavonoids
  • Flavanols
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