Dinatriumdihydrogen(dichloromethylen)diphosphonat
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- CAS-Nr.
- 22560-50-5
- Bezeichnung:
- Dinatriumdihydrogen(dichloromethylen)diphosphonat
- Englisch Name:
- Clodronate disodium Salt
- Synonyma:
- CLODRONATE DISODIUM;DMDP;Loron;CL2MDP;bm06011;U-82067E;lodronate;Difosfonal;clodronatesodium;sodiumclodronate
- CBNumber:
- CB0318011
- Summenformel:
- CH5Cl2NaO6P2
- Molgewicht:
- 268.88
- MOL-Datei:
- 22560-50-5.mol
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Dinatriumdihydrogen(dichloromethylen)diphosphonat Eigenschaften
- Schmelzpunkt:
- >330°C
- storage temp.
- room temp
- L?slichkeit
- Freely soluble in water, practically insoluble in ethanol (96 per cent), slightly soluble in methanol.
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Wasserl?slichkeit
- water: 49.00-51.00mg/mL, clear, colorless
- InChI
- InChI=1S/CH4Cl2O6P2.Na.H/c2-1(3,10(4,5)6)11(7,8)9;;/h(H2,4,5,6)(H2,7,8,9);;
- InChIKey
- HJKBJIYDJLVSAO-UHFFFAOYSA-L
- SMILES
- C(Cl)(Cl)(P(O)(O)=O)P(O)(O)=O.[NaH]
- CAS Datenbank
- 22560-50-5(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
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| RTECS-Nr. |
SZ7640700 |
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| HS Code |
29319090 |
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| Speicherklasse |
11 - Combustible Solids |
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| Toxizit?t |
mouse,LD50,intraperitoneal,780mg/kg (780mg/kg),British UK Patent Application. Vol. #2096889, |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Dinatriumdihydrogen(dichloromethylen)diphosphonat Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Clodronate disodium is a bone resorption inhibitor, useful as adjunct therapy in the treatment of osteolytic bone metastases and malignant hypercalcemia.
Chemische Eigenschaften
White Solid
Definition
ChEBI: The disodium salt of clodronic acid. It inhibits bone resorption and soft tissue calcification, and is used (generally as the tetrahydrate) as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteoly
ic lesions and bone pain associated with skeletal metastases.
Hazard
Moderately toxic by ingestion.
Sicherheitsprofil
A poison by intravenous route. Moderately toxic by ingestion, intraperitoneal routes. When heated to decomposition it emits toxic vapors of PO, and Cl-
Dinatriumdihydrogen(dichloromethylen)diphosphonat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Dinatriumdihydrogen(dichloromethylen)diphosphonat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 180)Lieferanten
22560-50-5(Dinatriumdihydrogen(dichloromethylen)diphosphonat)Verwandte Suche:
- CL2MDP
- Phosphonic acid, P,P'-(dichloromethylene)bis-, sodium salt (1:2)
- Clodronate disodium, >=98%
- DICHLOROMETHYLENEDIPHOPHONIC ACID DISODIUM SALT
- DICHLOROMETHYLENEDIPHOSPHONIC ACID DISODIUM SALT
- DMDP
- CLODRONIC ACID DISODIUM SALT
- (dichloromethylene)bis-phosphonicacidisodiumsalt
- (dichloromethylene)di-phosphonicacidisodiumsalt
- bm06011
- chlodronatesodium
- clodronatesodium
- dichloromethanediphosphonate
- disodium(dichloromethylene)bisphosphonate
- disodium [dichloro-[hydroxy(oxido)phosphoryl]methyl]-hydroxy-phosphinate
- Clodronic Acid, Disodium Salt, Hydrate
- disodiumclodronate
- lodronate
- sodiumclodronate
- Clodronate Disodium, Bonefos, Clasteon, Clastoban
- disodium dihydrogen (dichloromethylene)diphosphonate
- DICHLOROMETHYLENEDIPHOSPHONIC ACID
- ClodronateAcidDisodiumSalt
- clodronate disodium，CLD
- Difosfonal
- Loron
- (Dichloromethylene)bis(phosphonic acid hydrogen sodium) salt
- Disodium crodronate
- U-82067E
- disodium [dichloro-[hydroxy(oxidanidyl)phosphoryl]methyl]-hydroxy-phosphinate
- disodium [dichloro-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate
- clodronic acid, sodium salt
- Cl2MDP, Clodronic acid disodium salt, DMDP
- (Dichloromethylene)diphosphonate disodium
- disodium [dichloro(phosphonato)methyl]-dioxido-oxophosphorane
- clodronicaciddisodiumsal
- CAS22560-50-5 clodronic acid disodium salt
- Sodium (dichloro(phosphono)methyl)phosphonate
- CLODRONATE DISODIUM SALT
- CLODRONATE DISODIUM
- 22560-50-5
- CH2Cl2O6P22Na
- CH2Cl2Na2O6P2
- CH2O6Cl2Na2P2
- CH4Cl2O6P02Na
- Clodronic Acid Disodium
- Other APIs
- Inhibitors
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Phosphorylating and Phosphitylating Agents
- All Inhibitors
- 22560-50-5
