ANTI-SYNAPTOPHYSIN Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-Synaptophysin antibody produced in rabbit has been used in:
- immunocytochemistry
- western blotting
- immunohistochemistry
Allgemeine Beschreibung
Synaptophysin (SYP) is an integral membrane glycoprotein of 38,000 Da and it has four membrane-spanning domains. Synaptophysin is localized to neurons, neuromuscular junctions, paraganglia cells, hypophysis, pancreatic islet cells, and adrenal cells. SYP gene is mapped to human chromosome Xp11.23. Monoclonal Anti-Synaptophysin (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.
Biochem/physiol Actions
Synaptophysin (SYP) modulates neurotransmitter release and synaptic plasticity. It maintains biogenesis and recycling of synaptic vesicles. SYP functions as a marker for neuroendocrine tumors. It is used as a potent marker for neuroendocrine prostate cancer (NEPC). Mutations in this gene is associated with X-linked intellectual disability.
ANTI-SYNAPTOPHYSIN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
