N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanin
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- CAS-Nr.
- 35661-39-3
- Bezeichnung:
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanin
- Englisch Name:
- FMOC-Ala-OH
- Synonyma:
- FMOC-ALA;FMOC-L-ALA-OH;FMOC-L-ALANINE;FMOC-L-ALA;Fomc-Ala-OH;N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-ALANINE;Fmoc-AL;N-FMOC-L-ALANINE;(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid;Fmoc-DL-Alanine
- CBNumber:
- CB0396798
- Summenformel:
- C18H17NO4
- Molgewicht:
- 311.33
- MOL-Datei:
- 35661-39-3.mol
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N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanin Eigenschaften
- Schmelzpunkt:
- 147-153 °C (lit.)
- alpha
- -19 º (c=1,DMF)
- Siedepunkt:
- 451.38°C (rough estimate)
- Dichte
- 1.2626 (rough estimate)
- Brechungsindex
- -18.5 ° (C=1, DMF)
- storage temp.
- Store below +30°C.
- L?slichkeit
- DMSO (Slightly), DMF (Sparingly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 3.91±0.10(Predicted)
- Farbe
- White
- Optische Rotation
- [α]20/D 18°, c = 1 in DMF
- Wasserl?slichkeit
- Soluble in water.
- BRN
- 2225975
- Major Application
- peptide synthesis
- InChI
- 1S/C18H17NO4/c1-11(17(20)21)19-18(22)23-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,19,22)(H,20,21)/t11-/m0/s1
- InChIKey
- QWXZOFZKSQXPDC-NSHDSACASA-N
- SMILES
- C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
- CAS Datenbank
- 35661-39-3(CAS DataBase Reference)
- CAS Number Unlabeled
- 35661-39-3
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanin Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S27:Beschmutzte, getr?nkte Kleidung sofort ausziehen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
FMOC-Ala-OH is a versatile reagent used in Fmoc solid-phase peptide synthesis.
Chemische Eigenschaften
white to light yellow crystal powde
Verwenden
FMOC-Ala-OH is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Alanine is one of the simplest amino acids - a methyl group as the side chain. This small side chain confers a high degree of flexibility when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.
synthetische
A solution of the Fmoc-OX derivatives (20 mmol) in 100 mL acetone was added dropwise to a stirred solution of Alanine (20 mmol) and NaHCO
3 (50 mmol) in 100 mL water. After stirring overnight the reaction mixture was concentrated under reduced pressure and then extracted with CH
2Cl
2 (50 mL) to remove the unreacted Fmoc-OX derivatives. The reaction mixture was cooled and acidified with 10% HCl to congo red litmus paper to give a white solid, which was filtered and washed with water several times, dried to give a white solid (FMOC-Ala-OH).Yield=89.5%.
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 650)Lieferanten
35661-39-3(N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanin)Verwandte Suche:
- N-alpha-(9-fluorenylmethyloxycarbonyl)-L-alanine, anhydrous
- Fmoc-L-alanine≥ 99.7% (HPLC, Chiral purity)
- FMOC-ALA-OH
- FMOC-L-ALPHA-ALANINE
- N-(9-FLUORENYLMETHOXYCARBONYL)-L-ALPHA-ALANINE
- N-9-FLUORENYLMETHYLOXYCARBONYL-L-ALANINE
- N-(9-FLUORENYLMETHOXYCARBONYL)-L-ALANINE
- FMOC-L-alpha-Alanine,98%
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine Hydrate
- Fmoc-L-alanine
Fmoc-Ala-OH
- Fmoc-Ala-OH 95%
- (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propionic acid
- Fmoc-L-Alanine-OH
- FMoc-Ala-OH FMoc-L-Alanine
- N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-ALANINE
- N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-ALANINE
- N-ALPHA-FMOC-L-ALA
- N-ALPHA-FMOC-L-ALANINE
- L-ALANINE-2-13C, N-FMOC DERIV 99&
- Fmoc-L-alanine,98%
- L-Alanine-2-13C-N-FMOC
- Fmoc-amino acids and Derivatives
- N-(9-FLUORENYLMETHOXYCARBONYL)-L-ALANINE(FMOC-L-ALA-OH)
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine Monohydrate
- FMOC-L-ALANINE extrapure
- N-(9-Fluorenylmethoxycarbonyl)-L-alanine, Fmoc-L-alanine
- 2-(9H-Fluoren-9-ylmethoxycarbonylamino)propanoic acid
- L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
- N-(9-Fluorenylmethyloxycarbonyl)-L-alanine ,98%
- 9-FMOC-L-ALANINE
- (2S)-2-[(9H-fluoren-9-ylmethoxy-oxomethyl)amino]propanoic acid
- (2S)-2-(9H-Fluorene-9-ylmethoxycarbonylamino)propionic acid
- (2S)-2-[(9H-Fluorene-9-ylmethoxycarbonyl)amino]propanoic acid
- N-(9H-Fluorene-9-ylmethoxycarbonyl)alanine
- (9H-Fluoren-9-yl)MethOxy]Carbonyl Ala-OH
- Fmoc-Ala-OH| Fmoc-L-Ala-OH
- (-)-L-Alanine, N-FMOC protected
- (-)-L-Alanine, N-FMOC protected 95%
- (2S)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]propanoate
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanineHydrate>
- FMOC-ALA-OH 100 G
- FMOC-ALA-OH 250 G
- (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoicaci
- FMOC-Ala-OH USP/EP/BP
- Fmoc-L-alanine, puriss, 99%
- Fmoc-L-alanine,max.6%H2O
- (S)-2-(((9H-fluoren-9-yl)Methoxy)carbonylaMino)propanoic acid
- Fmoc-DL-Alanine
- N-fluoromethoxycarbonyl-L-alanine
- Fmoc-Ala-OH Hydrate
- (-)-L-Alanine, N-FMOC protected
- (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
- Fmoc-AL
- FMOC-ALA
- FMOC-L-ALA
- FMOC-L-ALA-OH
- FMOC-L-ALANINE
- Fomc-Ala-OH
