(RS)-(TETRAZOL-5-YL)GLYCINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Tetrazolyl glycine is an NMDA receptor agonist. It binds to rat brain membranes with IC₅₀ values of 98 and 36 nM for [³H]CGS19755 and [³H]glutamate, respectively, in radioligand binding assays. It induces depolarization in rat cortical slices, an effect that is blocked by the NMDA receptor antagonist LY233053. It induces degeneration of GABAergic and cholinergic neurons in the striatum of adult rats and the formation of excitotoxic lesions and seizures in neonatal rats (ED₅₀ = 0.071 mg/kg). Intrastriatal injection of tetrazolyl glycine (5 μM) increases COX-2 expression in striatal neurons and the vasculature near the striatal injection site in a mouse model of excitotoxicity-induced neuronal injury.

Verwenden

(RS)-(Tetrazol-5-yl)glycine is a highly potent NMDA receptor agonist demonstrating ~ 20X more activity than NMDA.

(RS)-(TETRAZOL-5-YL)GLYCINE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(RS)-(TETRAZOL-5-YL)GLYCINE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	+8617735180244	mike_yan@xuanranglobal.com	CHINA	4017	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43333	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
Nanjing Moldeep Biochemical Co., Ltd.	+86-25-58282389 +8618913958656	inquiries@moldeep.com	China	20000	58
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7750	56
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60

138199-51-6()Verwandte Suche:

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• (RS)-(TETRAZOL-5-YL)GLYCINE
• (tetrazol-5-yl)glycine
• 5-Tetrazolyl-glycine
• C13738
• Tet-glycine
• aMino(2H-tetrazol-5-yl)acetic acid
• Amino-(1H-tetrazol-5-yl)-acetic acid
• 2H-Tetrazole-5-acetic acid, a-amino-
• alpha-Amino-2H-tetrazole-5-acetic acid
• LY 285265
• 2H-Tetrazole-5-acetic acid, α-amino-
• (RS)-(Tetrazol-5-yl)
• 2-Amino-2-(2H-tetrazol-5-yl)acetic acid
• Tetrazolyl Glycine
• (RS)-(Tetrazol-5-yl)glycine/LY285265
• L-(tetrazol-5-yl)glycine
• Fos,iGluR,GluN2D,LY-285265,Ionotropic glutamate receptors,inhibit,Inhibitor,(RS)(Tetrazol5yl)glycine,GluN1,(RS) (Tetrazol 5 yl)glycine,GluN2A,LY285265,NMDA,seizure
• 138199-51-6