11-DEOXY-11-METHYLENE PROSTAGLANDIN D2
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- CAS-Nr.
- 100648-29-1
- Englisch Name:
- 11-DEOXY-11-METHYLENE PROSTAGLANDIN D2
- Synonyma:
- 11-Deoxy-11-methylene PGD2;ROZAFJXVUNORLT-SFIVEXQWSA-N;11-DEOXY-11-METHYLENE PROSTAGLANDIN D2;11-deoxy-11-methylene Prostaglandin D2;9ALPHA,15S-DIHYDROXY-11-METHYLENE-PROSTA-5Z,13E-DIEN-1-OIC ACID;Prosta-5,13-dien-1-oicacid,9,15-dihydroxy-11-methylene-,(5z,9a,13e,15s)-;Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-methylene-, (5Z,9α,13E,15S)-
- CBNumber:
- CB0448473
- Summenformel:
- C21H34O4
- Molgewicht:
- 350.49
- MOL-Datei:
- 100648-29-1.mol
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11-DEOXY-11-METHYLENE PROSTAGLANDIN D2 Eigenschaften
- L?slichkeit
- DMF: 100 mg/ml; DMSO: 100 mg/ml; Ethanol: 100 mg/ml; PBS (pH 7.2): 3.75 mg/ml
Sicherheit
11-DEOXY-11-METHYLENE PROSTAGLANDIN D2 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Prostaglandin D2 (PGD2; ) is one of the five primary enzymatic prostaglandins derived directly from PGH2 . PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second, leukocyte-type PGD synthase. 11-deoxy-11-methylene PGD2 is a novel, chemically stable, isosteric analog of PGD2 wherein the 11-keto group is replaced by an exocyclic methylene. In the PGE series, the analogous modification leads to a stable, somewhat less potent agonist which embodies the same uterine stimulant and cervical ripening activities as the parent prostaglandin. However, 11-deoxy-11-methylene PGD2 has been reported by one group to be essentially without agonist activity on human platelets, a DP1 receptor assay.
11-DEOXY-11-METHYLENE PROSTAGLANDIN D2 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
11-DEOXY-11-METHYLENE PROSTAGLANDIN D2 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 23)Lieferanten
- 9ALPHA,15S-DIHYDROXY-11-METHYLENE-PROSTA-5Z,13E-DIEN-1-OIC ACID
- 11-deoxy-11-methylene Prostaglandin D2
- 11-DEOXY-11-METHYLENE PROSTAGLANDIN D2
- ROZAFJXVUNORLT-SFIVEXQWSA-N
- Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-methylene-, (5Z,9α,13E,15S)-
- Prosta-5,13-dien-1-oicacid,9,15-dihydroxy-11-methylene-,(5z,9a,13e,15s)-
- 11-Deoxy-11-methylene PGD2
- 100648-29-1