KEA1-97

2138882-71-8

CAS-Nr.: 2138882-71-8

Englisch Name:: KEA1-97

Synonyma:: KEA1-97;KEA1-97 >=98% (HPLC);KEA1-97, 10 mM in DMSO;4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine;1,3,5-Triazin-2-amine, 4,6-dichloro-N-(4'-fluoro[1,1'-biphenyl]-4-yl)-;Apoptosis,KEA1 97,Proliferation,Apoptotic,Caspase,inhibit,KEA-1-97,DCTalkyne,KEA1-97,231MFP,Inhibitor,Selective,KEA197

CBNumber:: CB04668109

Summenformel:: C15H9Cl2FN4

Molgewicht:: 335.16

MOL-Datei:: 2138882-71-8.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 41

KEA1-97 Eigenschaften

Siedepunkt:: 530.3±52.0 °C(Predicted)

Dichte: 1.466±0.06 g/cm3(Predicted)

storage temp.: 4°C, protect from light

L?slichkeit: DMSO : 100 mg/mL (298.36 mM; Need ultrasonic)

pka: 0.57±0.10(Predicted)

Aggregatzustand: Solid

Farbe: White to light yellow

InChI: InChI=1S/C15H9Cl2FN4/c16-13-20-14(17)22-15(21-13)19-12-7-3-10(4-8-12)9-1-5-11(18)6-2-9/h1-8H,(H,19,20,21,22)

InChIKey: DUROVTLUQOYUPH-UHFFFAOYSA-N

SMILES: N1=C(Cl)N=C(Cl)N=C1NC1=CC=C(C2=CC=C(F)C=C2)C=C1

Sicherheit

WGK Germany	WGK 3
Speicherklasse	11 - Combustible Solids

KEA1-97 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

KEA1-97 is a Thioredoxin-Caspase 3 interaction disruptor. It was found to target lysine 72 of thioredoxin, inhibiting its interactions with caspase 3 and inducing apoptosis without affecting other thioredoxin activity. KEA1-97 induced apoptosis in breast cancer cells and treatment of immune-deficient SCID mice at 5 mg/kg ip impaired breast tumor xenograft growth.

KEA1-97 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

KEA1-97 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 41)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3135	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39037	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16101	64
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4849	55
Shanghai YuanYe Biotechnology Co., Ltd.	13636370518	shyysw007@163.com	China	89686	60
ShangHai Biochempartner Co.,Ltd	177-54423994 17754423994	2853530910@QQ.com	China	8000	62

KEA1-97
1,3,5-Triazin-2-amine, 4,6-dichloro-N-(4'-fluoro[1,1'-biphenyl]-4-yl)-
KEA1-97 >=98% (HPLC)
4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine
Apoptosis,KEA1 97,Proliferation,Apoptotic,Caspase,inhibit,KEA-1-97,DCTalkyne,KEA1-97,231MFP,Inhibitor,Selective,KEA197
KEA1-97, 10 mM in DMSO
2138882-71-8
C15H9Cl2FN4

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