XESTOSPONGIN C Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Xestospongin C is a marine natural product which was first isolated from Pacific basin sponges, and noted to have vasodilatory properties. Xestospongin C antagonizes the calcium-releasing action of inositol-1,4,5-trisphosphate (IP3) at the receptor level. Inositol phosphates are important signal transduction messengers acting via IP3 receptors to promote the mobilization of Ca2+ from intracellular stores. Xestospongin C blocks the increase in intracellular calcium in vascular smooth muscle cells completely at a concentration of 25 μM. Xestospongin C also inhibits the sarcoplasmic reticulum Ca2+ ATPase pump at concentrations of 700 nM.
Definition
ChEBI: An organic heteropentacyclic compound that is isolated from the marine sponge Xestospongia exigua.
Allgemeine Beschreibung
Synthetic form of the macrocyclic bis-1-oxaquinolizidine isolated from the Okanowan marine sponge.
XESTOSPONGIN C Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
